ИСТОРИЯ ИЗУЧЕНИЯ ЮВЕНИЛЬНОЙ ФИБРОМИАЛГИИ: К 40-ЛЕТИЮ ПЕРВОГО ОПИСАНИЯ. ЧАСТЬ I. ЭПИДЕМИОЛОГИЯ, ЭТИОЛОГИЯ И ПАТОГЕНЕЗ, ДИАГНОСТИЧЕСКИЕ КРИТЕРИИ
Аннотация
Muhammad B. Yunus и Alfonse T. Masi в феврале 1985 года впервые описали 33 случая ювенильной первичной фибромиалгии (ФМ) и предложили ее диагностические критерии, однако и 40 лет спустя практикующие врачи зачастую испытывают затруднения при ее диагностике и лечении. Это во многом связано с недостаточной информированностью детских врачей о данной проблеме, так как в доступной зарубежной литературе информации о ювенильной фибромиалгии (ЮФМ) существенно меньше, чем о ФМ у взрослых пациентов, а в русскоязычных научных статьях вопросы ЮФМ практически не обсуждаются. Большинство опубликованных ранее обзоров литературы, посвященных ЮФМ, как правило, приводят информацию не только непосредственно о ней, но и, в большей степени, о ФМ у взрослых, что не вполне корректно, так как существует целый ряд уникальных особенностей ЮФМ и ее отличий от ФМ у взрослых. Цель настоящего обзора — обобщить оригинальные исследования ЮФМ, избегая ссылок на исследования с участием только взрослых пациентов. В части I статьи приведены данные о диагностических критериях, эпидемиологии, этиологии и патогенезе ЮФМ.
Литература
Yunus M.B., Masi A.T. Juvenile primary fibromyalgia syndrome. A clinical study of thirty-three patients and matched normal controls. Arthritis Rheum. 1985;28(2):138–45. DOI: 10.1002/art.1780280205.
Сантимов А.В. Структура установленных диагнозов и назначенной терапии у пациентов различных возрастных групп на амбулаторных приемах врача-ревматолога в течение двух лет. Университетский терапевтический вестник. 2024;6(1):126–138. DOI: 10.56871/UTJ.2024.69.36.012.
Сантимов А.В., Тамм О.А. Вопросы оказания амбулаторной ревматологической помощи детям в Санкт-Петербурге (на примере Детской городской больницы № 2 Святой Марии Магдалины). 2024;12(3):121–129. DOI: 10.56871/CmN-W.2024.77.77.014.
Сантимов А.В., Гречаный С.В., Новик Г.А. Вторичная фибромиалгия у детей с иммуновоспалительными ревматическими заболеваниями. Современная ревматология. 2024;18(3):99–106. DOI: 10.14412/1996-7012-2024-3-99-106.
Сантимов А.В., Гречаный С.В., Новик Г.А. Нарушения психического здоровья у детей с ревматическими заболеваниями. Научно-практическая ревматология. 2024;62(1):109–117. DOI: 10.47360/1995-4484-2024-109-117.
Wolfe F., Smythe H.A., Yunus M.B. et al. The American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia. Report of the Multicenter Criteria Committee. Arthritis Rheum. 1990;33(2):160–72. DOI: 10.1002/art.1780330203.
Buskila D., Press J., Gedalia A. et al. Assessment of nonarticular tenderness and prevalence of fibromyalgia in children. J Rheumatol. 1993;20(2):368–70.
Swain N.F., Kashikar-Zuck S., Graham T.B., Prahalad S. Tender point assessment in juvenile primary fibromyalgia syndrome. Arthritis Rheum. 2005;53(5):785–7. DOI: 10.1002/art.21442.
Wolfe F., Clauw D.J., Fitzcharles M.A. et al. The American College of Rheumatology preliminary diagnostic criteria for fibromyalgia and measurement of symptom severity. Arthritis Care Res (Hoboken). 2010;62(5):600–10. DOI: 10.1002/acr.20140.
Ting T.V., Barnett K., Lynch-Jordan A. et al. 2010 American College of Rheumatology Adult Fibromyalgia Criteria for Use in an Adolescent Female Population with Juvenile Fibromyalgia. J Pediatr. 2016;169:181–7.e1. DOI: 10.1016/j.jpeds.2015.10.011.
Wolfe F., Clauw D.J., Fitzcharles M.A. et al. 2016 Revisions to the 2010/2011 fibromyalgia diagnostic criteria. Semin Arthritis Rheum. 2016;46(3):319–329. DOI: 10.1016/j.semarthrit.2016.08.012.
Peterson E.E., Yao C., Sule S.D., Finkel J.C. The Challenges of Identifying Fibromyalgia in Adolescents. Case Rep Pediatr. 2022;2022:8717818. DOI: 10.1155/2022/8717818.
Sardini S., Ghirardini M., Betelemme L. et al. Studio epidemiologico sulla fibromialgia primaria in età pediatrica [Epidemiological study of a primary fibromyalgia in pediatric age]. Minerva Pediatr. 1996;48(12):543–550. (In Italian).
Mikkelsson M., Sourander A., Piha J., Salminen J.J. Psychiatric symptoms in preadolescents with musculoskeletal pain and fibromyalgia. Pediatrics. 1997;100(2 Pt 1):220–7. DOI: 10.1542/peds.100.2.220.
Clark P., Burgos-Vargas R., Medina-Palma C. et al. Prevalence of fibromyalgia in children: a clinical study of Mexican children. J Rheumatol. 1998;25(10):2009–2014.
Durmaz Y., Alayli G., Canbaz S. et al. Prevalence of juvenile fibromyalgia syndrome in an urban population of Turkish adolescents: impact on depressive symptoms, quality of life and school performance. Chin Med J (Engl). 2013;126(19):3705–3711.
Çagliyan TÜrk A., Şahİn F. Prevalence of Juvenile Fibromyalgia Syndrome Among Children and Adolescents and its Relationship With Academic Success, Depression and Quality of Life, Çorum Province, Turkey. Arch Rheumatol. 2019;35(1):68–77. DOI: 10.5606/ArchRheumatol.2020.7458.
Maddali Bongi S., Vitali Rosati G., Bonaccorsi G., Lorini C. Prevalence and Contextual Factors of Juvenile Fibromyalgia in a Population-Based Italian Sample of Children and Adolescents. Biomedicines. 2023;11(6):1583. DOI: 10.3390/biomedicines11061583.
Buskila D., Neumann L., Hazanov I., Carmi R. Familial aggregation in the fibromyalgia syndrome. Semin Arthritis Rheum. 1996;26(3):605–11. DOI: 10.1016/s0049-0172(96)80011-4.
Roizenblatt S., Tufik S., Goldenberg J. et al. Juvenile fibromyalgia: clinical and polysomnographic aspects. J Rheumatol. 1997;24(3):579–85.
Gedalia A., Press J., Klein M., Buskila D. Joint hypermobility and fibromyalgia in schoolchildren. Ann Rheum Dis. 1993;52(7):494–6. DOI: 10.1136/ard.52.7.494.
Gedalia A., García C.O., Molina J.F. et al. Fibromyalgia syndrome: experience in a pediatric rheumatology clinic. Clin Exp Rheumatol. 2000;18(3):415–419.
Siegel D.M., Janeway D., Baum J. Fibromyalgia syndrome in children and adolescents: clinical features at presentation and status at follow-up. Pediatrics. 1998;101(3 Pt 1):377–82. DOI: 10.1542/peds.101.3.377.
Ting T.V., Hashkes P.J., Schikler K. et al. The role of benign joint hypermobility in the pain experience in Juvenile Fibromyalgia: an observational study. Pediatr Rheumatol Online J. 2012;10(1):16. DOI: 10.1186/1546-0096-10-16.
Şahin N.Ü., Şahin N., Kılıç M. Effect of comorbid benign joint hypermobility and juvenile fibromyalgia syndromes on pediatric functional gastrointestinal disorders. Postgrad Med. 2023;135(4):386–393. DOI: 10.1080/00325481.2023.2176637.
Black W.R., DiCesare C.A., Wright L.A. et al. The effects of joint hypermobility on pain and functional biomechanics in adolescents with juvenile fibromyalgia: secondary baseline analysis from a pilot randomized controlled trial. BMC Pediatr. 2023;23(1):557. DOI: 10.1186/s12887-023-04353-y.
Suñol M., Payne M.F., Tong H. et al. Brain Structural Changes During Juvenile Fibromyalgia: Relationships With Pain, Fatigue, and Functional Disability. Arthritis Rheumatol. 2022;74(7):1284–1294. DOI: 10.1002/art.42073.
Tong H., Maloney T.C., Payne M.F. et al. Augmented pain-evoked primary sensorimotor cortex activation in adolescent girls with juvenile fibromyalgia. Pain. 2023;164(10):2316–2326. DOI: 10.1097/j.pain.0000000000002933.
Suñol M., Dudley J., Payne M.F., Tong et al. Reduced Cortico-Cortical Resting-State Connectivity in Sensory Systems Related to Bodily Pain in Juvenile Fibromyalgia. Arthritis Rheumatol. 2024;76(2):293–303. DOI: 10.1002/art.42691.
Suñol M., Pascual-Diaz S., Dudley J. et al. Neurophysiology of Resilience in Juvenile Fibromyalgia. medRxiv [Preprint]. 2024:2024.06.05.24308376. DOI: 10.1101/2024.06.05.24308376.
Boneparth A., Chen S., Horton D.B. et al. Epidermal Neurite Density in Skin Biopsies From Patients With Juvenile Fibromyalgia. J Rheumatol. 2021;48(4):575–578. DOI: 10.3899/jrheum.200378.
Bell D.S., Bell K.M., Cheney P.R. Primary juvenile fibromyalgia syndrome and chronic fatigue syndrome in adolescents. Clin Infect Dis. 1994;18(Suppl 1):S21–3. DOI: 10.1093/clinids/18.supplement_1.s21.
Varni J.W., Burwinkle T.M., Szer I.S. The PedsQL Multidimensional Fatigue Scale in pediatric rheumatology: reliability and validity. J Rheumatol. 2004;31(12):2494–500.
Varni J.W., Burwinkle T.M., Limbers C.A., Szer I.S. The PedsQL as a patient-reported outcome in children and adolescents with fibromyalgia: an analysis of OMERACT domains. Health Qual Life Outcomes. 2007;5:9. DOI: 10.1186/1477-7525-5-9.
Gmuca S., Sonagra M., Xiao R. et al. Characterizing Neurocognitive Impairment in Juvenile Fibromyalgia Syndrome: Subjective and Objective Measures of Dyscognition. Front Pediatr. 2022;10:848009. DOI: 10.3389/fped.2022.848009.
Tayag-Kier C.E., Keenan G.F., Scalzi L.V. et al. Sleep and periodic limb movement in sleep in juvenile fibromyalgia. Pediatrics. 2000;106(5):E70. DOI: 10.1542/peds.106.5.e70.
Olsen M.N., Sherry D.D., Boyne K. et al. Relationship between sleep and pain in adolescents with juvenile primary fibromyalgia syndrome. Sleep. 2013;36(4):509–16. DOI: 10.5665/sleep.2534.
Malattia C., Chiarella L., Sansone M. et al. Sleep and Sleep Complaints in Juvenile Fibromyalgia Syndrome. J Rheumatol. 2023;50(6):827–834. DOI: 10.3899/jrheum.220720.
King C.D., Jastrowski Mano K.E., Barnett K.A. et al. Pressure Pain Threshold and Anxiety in Adolescent Females With and Without Juvenile Fibromyalgia: A Pilot Study. Clin J Pain. 2017;33(7):620–626. DOI: 10.1097/AJP.0000000000000444.
de Tommaso Tommaso M., Sciruicchio V., Delussi M. et al. Symptoms of central sensitization and comorbidity for juvenile fibromyalgia in childhood migraine: an observational study in a tertiary headache center. J Headache Pain. 2017;18(1):59. DOI: 10.1186/s10194-017-0764-8.
Mansiz-Kaplan B., Ayhan F.F., Cagli M. et al. A preliminary study of the child abuse and central sensitization in adolescent patients with chronic non-organic chest pain and an overlooked condition: juvenile fibromyalgia syndrome. Pediatr Rheumatol Online J. 2020;18(1):28. DOI: 10.1186/s12969-020-00421-0.
Vandvik I.H., Forseth K.O. A bio-psychosocial evaluation of ten adolescents with fibromyalgia. Acta Paediatr. 1994;83(7):766–71. DOI: 10.1111/j.1651-2227.1994.tb13135.x.
Schanberg L.E., Keefe F.J., Lefebvre J.C. et al. Pain coping strategies in children with juvenile primary fibromyalgia syndrome: correlation with pain, physical function, and psychological distress. Arthritis Care Res. 1996;9(2):89–96. DOI: 10.1002/1529-0131(199604)9:2<89::aid-anr1790090204>3.0.co;2-j.
Reid G.J., Lang B.A., McGrath P.J. Primary juvenile fibromyalgia: psychological adjustment, family functioning, coping, and functional disability. Arthritis Rheum. 1997;40(4):752–60. DOI: 10.1002/art.1780400423.
Schanberg L.E., Keefe F.J., Lefebvre J.C. et al. Social context of pain in children with Juvenile Primary Fibromyalgia Syndrome: parental pain history and family environment. Clin J Pain. 1998;14(2):107–15. DOI: 10.1097/00002508-199806000-00004.
Kashikar-Zuck S., Vaught M.H., Goldschneider K.R. et al. Depression, coping, and functional disability in juvenile primary fibromyalgia syndrome. J Pain. 2002;3(5):412–9. DOI: 10.1054/jpai.2002.126786.
Conte P.M., Walco G.A., Kimura Y. Temperament and stress response in children with juvenile primary fibromyalgia syndrome. Arthritis Rheum. 2003;48(10):2923–30. DOI: 10.1002/art.11244.
Seng J.S., Graham-Bermann S.A., Clark M.K., McCarthy A.M., Ronis D.L. Posttraumatic stress disorder and physical comorbidity among female children and adolescents: results from service-use data. Pediatrics. 2005;116(6):e767–76. DOI: 10.1542/peds.2005-0608.
Reid G.J., McGrath P.J., Lang B.A. Parent-child interactions among children with juvenile fibromyalgia, arthritis, and healthy controls. Pain. 2005;113(1-2):201–10. DOI: 10.1016/j.pain.2004.10.018.
Kashikar-Zuck S., Lynch A.M., Graham T.B. et al. Social functioning and peer relationships of adolescents with juvenile fibromyalgia syndrome. Arthritis Rheum. 2007;57(3):474–80. DOI: 10.1002/art.22615.
Kashikar-Zuck S., Lynch A.M., Slater S. et al. Family factors, emotional functioning, and functional impairment in juvenile fibromyalgia syndrome. Arthritis Rheum. 2008;59(10):1392–8. DOI: 10.1002/art.24099.
Kashikar-Zuck S., Parkins I.S., Graham T.B. et al. Anxiety, mood, and behavioral disorders among pediatric patients with juvenile fibromyalgia syndrome. Clin J Pain. 2008;24(7):620–6. DOI: 10.1097/AJP.0b013e31816d7d23.
Lommel K., Kapoor S., Bamford J. et al. Juvenile primary fibromyalgia syndrome in an inpatient adolescent psychiatric population. Int J Adolesc Med Health. 2009;21(4):571–9. DOI: 10.1515/ijamh.2009.21.4.571.
Libby C.J., Glenwick D.S. Protective and exacerbating factors in children and adolescents with fibromyalgia. Rehabil Psychol. 2010;55(2):151–158. DOI: 10.1037/a0019518.
Kashikar-Zuck S., Johnston M., Ting T.V. et al. Relationship between school absenteeism and depressive symptoms among adolescents with juvenile fibromyalgia. J Pediatr Psychol. 2010;35(9):996–1004. DOI: 10.1093/jpepsy/jsq020.
Lommel K., Bamford J., Jhavari M. et al. A pilot study: pain, fatigue and stress in maternal relatives of adolescent female psychiatric inpatients assessed for juvenile primary fibromyalgia syndrome. Int J Adolesc Med Health. 2011;23(1):59–63. DOI: 10.1515/ijamh.2011.010.
Sil S., Lynch-Jordan A., Ting T.V. et al. Influence of family environment on long-term psychosocial functioning of adolescents with juvenile fibromyalgia. Arthritis Care Res (Hoboken). 2013;65(6):903–9. DOI: 10.1002/acr.21921.
Kashikar-Zuck S., Zafar M., Barnett K.A. et al. Quality of life and emotional functioning in youth with chronic migraine and juvenile fibromyalgia. Clin J Pain. 2013;29(12):1066–72. DOI: 10.1097/AJP.0b013e3182850544.
Offenbächer M., Kohls N., Walker L. et al. Functional limitations in children and adolescents suffering from chronic pain: validation and psychometric properties of the German Functional Disability Inventory (FDI-G). Rheumatol Int. 2016;36(10):1439–48. DOI: 10.1007/s00296-016-3504-5.
Miyamae T., Chiba Y., Kato I. et al. Neurodevelopmental disorders associated with juvenile fibromyalgia. Pediatr Int. 2018;60(11):1034–1035. DOI: 10.1111/ped.13696.
Fraga M.M., Terreri M.T., Azevedo R.T. et al. Pain perception and pain coping mechanisms in children and adolescents with juvenile fibromyalgia and polyarticular juvenile idiopathic arthritis. Rev Paul Pediatr. 2019;37(1):11–19. DOI: 10.1590/1984-0462/;2019;37;1;00006.
Gmuca S., Xiao R., Sherry D.D. Patient-proxy agreement on health-related quality of life in juvenile fibromyalgia syndrome. Pediatr Rheumatol Online J. 2019;17(1):21. DOI: 10.1186/s12969-019-0320-y.
Gmuca S., Sonagra M., Xiao R. et al. Suicidal risk and resilience in juvenile fibromyalgia syndrome: a cross-sectional cohort study. Pediatr Rheumatol Online J. 2021;19(1):3. DOI: 10.1186/s12969-020-00487-w.
Boileau N.R., Thompson-Phillips K.A., Goodin B.R. et al. Pain-Related Stigma and Its Associations With Clinical and Experimental Pain Severity in Youth With Chronic Musculoskeletal Pain Conditions. J Pediatr Psychol. 2023;48(10):842–851. DOI: 10.1093/jpepsy/jsad048.
Deere K.C., Clinch J., Holliday K. et al. Obesity is a risk factor for musculoskeletal pain in adolescents: findings from a population-based cohort. Pain. 2012;153(9):1932–1938. DOI: 10.1016/j.pain.2012.06.006.
da Silva S.G., Sarni R.O., de Souza F.I. et al. Assessment of nutritional status and eating disorders in female adolescents with fibromyalgia. J Adolesc Health. 2012;51(5):524–7. DOI: 10.1016/j.jadohealth.2012.02.018.
Miyamae T., Seki M., Naga T. et al. Increased oxidative stress and coenzyme Q10 deficiency in juvenile fibromyalgia: amelioration of hypercholesterolemia and fatigue by ubiquinol-10 supplementation. Redox Rep. 2013;18(1):12–9. DOI: 10.1179/1351000212Y.0000000036.
Miyamae T., Isozaki J., Kikuchi M., Yokota S. Eating Disorder in Juvenile Fibromyalgia. J Child Adolesc Psychopharmacol. 2016;26(7):653–5. DOI: 10.1089/cap.2014.0136.
Martínez-Lavín M. Fibromyalgia-like illness in 2 girls after human papillomavirus vaccination. J Clin Rheumatol. 2014;20(7):392–3. DOI: 10.1097/RHU.0000000000000165.
Agmon-Levin N., Zafrir Y., Kivity S. et al. Chronic fatigue syndrome and fibromyalgia following immunization with the hepatitis B vaccine: another angle of the 'autoimmune (auto-inflammatory) syndrome induced by adjuvants' (ASIA). Immunol Res. 2014;60(2-3):376–83. DOI: 10.1007/s12026-014-8604-2.
Nelson S., Cunningham N., Peugh J. et al. Clinical Profiles of Young Adults With Juvenile-Onset Fibromyalgia With and Without a History of Trauma. Arthritis Care Res (Hoboken). 2017;69(11):1636–1643. DOI: 10.1002/acr.23192.
Voepel-Lewis T., Caird M.S., Tait A.R. et al. A High Preoperative Pain and Symptom Profile Predicts Worse Pain Outcomes for Children After Spine Fusion Surgery. Anesth Analg. 2017;124(5):1594–1602. DOI: 10.1213/ANE.0000000000001963.
Басанцова Н.Ю., Зинченко Ю.С., Старшинова А.А., Яблонский П.К. Особенности диагностики нейропатий малых волокон при различных заболеваниях (обзор литературы). Педиатр. 2018;9(6):101–110. DOI: 10.17816/PED96101-110.
Шабалов Н.П., Иванов Д.О., Цыбулькин Э.К. и др. Неонатология. Том 2. М.: МЕДпресс-информ; 2004. EDN: QLGBMN.
Chokshi S.N., Mudiganty S., Clement R.C. 3rd, Accousti W. Vitamin D deficiency in Scheuermann's disease is associated with increased adverse outcomes. SICOT J. 2024;10:13. DOI: 10.1051/sicotj/2024010.