SYSTEMIC OSTEOPOROSIS AND PERIODONTAL BONE PATHOLOGY: PATHOGENETIC RELATIONSHIPS, STATISTICAL CORRELATIONS, SIGNIFICANCE FOR CLINICAL PRACTICE

  • M.M. Zabezhinskiy Saint-Petersburg State Pediatric Medical University 194100, Saint-Рetersburg
  • M.I. Muzykin Military Medical Academy named after S.M. Kirov 194044, Saint-Рetersburg
  • A.K. Iordanishvili Military Medical Academy named after S.M. Kirov 194044, Saint-Рetersburg
  • A.V. Vasil'eva Saint-Petersburg State Pediatric Medical University 194100, Saint-Рetersburg
Keywords: systemic osteoporosis, periodontal bone tissue, bone mineral density, experimental models, pathogenetic relationships

Abstract

Systemic osteoporosis (OP) is one of the socially significant diseases leading to the occurrence of pathological fractures that increase the level of disability and mortality. In most cases, the diagnosis of OP is made late, i.e. after the occurrence of a pathological fracture. It is highly important to search for markers for early detection of OP. Periodontal bone damage is pathogenetically closely related to systemic OP. This is evidenced by the data of experimental and numerous clinical and epidemiological studies. Pathology of periodontal bone tissue can be a consequence of OP and, in turn, by the mechanism of positive feedback to weigh down its course. Detection by the dentist of the pathology of the bone tissue of periodont, especially in postmenopausal women, can be considered as a marker that allows you to suspect systemic OP. An urgent problem is the absence in modern manuals and guidelines on OP of references to the pathology of the dental and jawbone system and pathogenetic links with OP. To improve the early diagnosis of OP, it is necessary to establish closer interaction between dentists and doctors of other specialties treating OP.

Author Biographies

M.M. Zabezhinskiy, Saint-Petersburg State Pediatric Medical University 194100, Saint-Рetersburg

Litovskaya str., 2; Candidate of Sciences in Medicine, Associate Professor of the Department of Pathological Physiology with the course of Immunopathology.

M.I. Muzykin, Military Medical Academy named after S.M. Kirov 194044, Saint-Рetersburg

Academician Lebedev str., 6

A.K. Iordanishvili, Military Medical Academy named after S.M. Kirov 194044, Saint-Рetersburg

Academician Lebedev str., 6

A.V. Vasil'eva, Saint-Petersburg State Pediatric Medical University 194100, Saint-Рetersburg

Litovskaya str., 2

Published
2021-11-22
How to Cite
Zabezhinskiy, M., Muzykin, M., Iordanishvili, A., & Vasil’eva, A. (2021). SYSTEMIC OSTEOPOROSIS AND PERIODONTAL BONE PATHOLOGY: PATHOGENETIC RELATIONSHIPS, STATISTICAL CORRELATIONS, SIGNIFICANCE FOR CLINICAL PRACTICE. Russian Biomedical Research, 6(3), 27-35. Retrieved from https://ojs3.gpmu.org/index.php/biomedical-research/article/view/2992
Section
Статьи

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