PREDICTION OF THE RISK OF CEREBRAL COMPLICATIONS AMONG CHILDREN WITH INFECTIONS LESIONS OF THE CENTRAL NERVOUS SYSTEM OF VARIOUS ETIOLOGIES

Abstract

Infectious lesions of the nervous system occupy 40% of the cohort of neurological diseases of childhood. Often severe course increases the risk of complications and disability. The work investigated cerebral disorders in children against the background of bacterial, viral meningoencephalitis, toxic encephalopathy, as well as damage to the nervous system in a new coronavirus infection. Based on the formed groups, the data of clinical blood analysis, biochemical blood analysis, clinical analysis of cerebrospinal fluid, integral leukocyte indices, SOFA scale data, ROX index and oxygenation index were studied. Using the method of multifactorial binary logistic regression analysis with step - by - step inclusion of independent variables, mathematical models for predicting the risk of cerebral complications in each of the three groups, depending on the etiology, were formed. The model includes variables available to the practitioner throughout the treatment, the selected values do not require additional expensive analyses or equipment, which is of great practical importance.