THE EFFECT OF KISSPEPTIN ON THE BEHAVIOR OF MALE RATS IN THE «OPEN FIELD» TEST

Abstract

The aim of the work is to study the nature of the behavioral reactions of rats in test tasks with intranasal administration of kisspeptin. To analyze the effect of kisspeptin on the behavioral response of rats in the «Open Field» test. In the process of work, research methods were used: testing rats in the «Open Field» test, methods of mathematical statistics. As a result of the work, it was determined that kisspeptin affects the behavioral responses of rats in new (stressful) conditions. In the experiment conducted with the use of the Open Field test setup, new data were obtained on the behavioral characteristics of rats under conditions of pharmacological activation of kisspeptin-energy receptors. It is noted that kisspeptin activates motor, exploratory activity, causes an anti-anxiety effect and the likelihood of cases of memory infection. The results presented in this article indicate a high frequency of hormonal effects of kisspeptin receptors on exploratory responses, anxiety levels, and memory.