РОЛЬ ЛИПИДОВ СЫВОРОТКИ КРОВИ В РАЗВИТИИ ЖЕЛЧНОКАМЕННОЙ БОЛЕЗНИ

Юрий Павлович Успенский; Юлия Александровна Фоминых; Кямаля Низамитдиновна Наджафова; Антон Викторович Кощеев; Флора Миргалимовна Султанова

Юрий Павлович Успенский St. Petersburg Pediatric Medical University; St. Petersburg State Medical University named after I.P. Pavlov 194100, St. Petersburg; 197022 Russia St. Petersburg
Юлия Александровна Фоминых St. Petersburg State Medical University named after I.P. Pavlov 197022 Russia St. Petersburg
Кямаля Низамитдиновна Наджафова St. Petersburg Pediatric Medical University 194100, St. Petersburg
Антон Викторович Кощеев North-Western State Medical University named after I.I. Mechnikov; Elizavetinskaya hospital 191015, Russia, St.Petersburg; 195257, St. Petersburg
Флора Миргалимовна Султанова Elizavetinskaya hospital 195257, St. Petersburg

Keywords: gallstone disease, lipid metabolism, cholecystectomy, metabolic syndrome

Abstract

Gallstones is a complex disease, the causes of its occurrence are not fully understood. There are described cholelithiasis risk factors, and the role of the metabolic syndrome in this process. This article presents a review of literature data on the role of serum lipids in the formation of gallbladder stones. We have discussed possible pathogenetic mechanisms, which demonstrate direct and inverse relationships between the development of gallstone disease and fractions of the blood lipid spectrum. The data of published clinical research about the relationship between the content of serum lipids and the risk of cholelithiasis are almost presented. Research data on the effect of cholecystectomy on lipid metabolism are also presented. There are formulated discussion questions requiring further studying for development of optimal methods of management of this category of patients.

Author Biographies

Юрий Павлович Успенский, St. Petersburg Pediatric Medical University; St. Petersburg State Medical University named after I.P. Pavlov 194100, St. Petersburg; 197022 Russia St. Petersburg

Litovskaya street, 2.; L’va Tolstogo street, 6-8.

Юлия Александровна Фоминых, St. Petersburg State Medical University named after I.P. Pavlov 197022 Russia St. Petersburg

L’va Tolstogo street, 6-8.

Кямаля Низамитдиновна Наджафова, St. Petersburg Pediatric Medical University 194100, St. Petersburg

Litovskaya street, 2.; senior medical laboratory assistant of Department of faculty therapy named after professor V.A. Valdman

Антон Викторович Кощеев, North-Western State Medical University named after I.I. Mechnikov; Elizavetinskaya hospital 191015, Russia, St.Petersburg; 195257, St. Petersburg

Kirochnaya street, 41; 14 vavilovykh str., Litera A

Флора Миргалимовна Султанова, Elizavetinskaya hospital 195257, St. Petersburg

14 vavilovykh str., Litera A

THE ROLE OF SERUM LIPIDS IN THE DEVELOPMENT OF GALLSTONE disease

Abstract

Author Biographies