Differences in sensitization to allergens in children with bronchial asthma living in areas with different levels of atmospheric air pollution

Abstract

Research objective: study of differences in the level and spectrum of sensitization in children suffering from moderate bronchial asthma (BA) and living in areas with different levels of atmospheric air pollution. Materials and methods: the study included 117 children (average age - 5.33±0.27 years), 77 boys (66%) and 40 girls (44%). In all children, the level of general and specific IgE for five groups of allergens (food, household, pollen, epidermal and fungal) was studied. Depending on the area of residence, the children were divided into 2 groups: from environmentally friendly areas and environmentally disadvantaged. Results: the examined children of both groups were characterized by polyvalent sensitization, but there were no statistically significant differences in the degree of sensitization to the allergen groups. However, patients from environmentally disadvantaged areas had significantly higher values of total IgE. Conclusions: the revealed differences in the level of total serum IgE in children suffering from BA and living in areas with different levels of atmospheric air pollution indicate a possible effect of aeropollutants on the state of the immune system of children.