THE ROLE OF HELICOBACTER PYLORI INFECTION AND CANDIDA SPP. IN THE PATHOGENESIS OF METABOLIC SYNDROME

  • Yury P Uspenskiy Saint-Petersburg State Pediatric Medical University; First Saint-Petersburg State Medical University named after academician I.P. Pavlov 194100, Saint-Рetersburg; 197022, Saint-Petersburg
  • Irina A Gorbacheva First Saint-Petersburg State Medical University named after academician I.P. Pavlov 197022, Saint-Petersburg
  • Yulia A Fominykh Saint-Petersburg State Pediatric Medical University; First Saint-Petersburg State Medical University named after academician I.P. Pavlov 194100, Saint-Рetersburg; 197022, Saint-Petersburg
  • Natalia V Baryshnikova First Saint-Petersburg State Medical University named after academician I.P. Pavlov; Institute for Experimental Medicine 197022, Saint-Petersburg; 197376, Saint-Petersburg
  • Mikhail A Shevyakov North-Western State Medical University named after I.I. Mechnikov 191015, Saint-Petersburg; 195067, Saint-Petersburg
Keywords: metabolic syndrome, fungi of the genus Candida, obesity, Helicobacter pylori

Abstract

The article discusses the possible pathogenetic mechanisms of the formation of metabolic disorders and metabolic syndrome in the conditions of long term persistence of infectious agents in the human body, such as Helicobacter pylori and yeast like fungi of the genus Candida. The variants of the influence of Helicobacter pylori infection on the development of obesity, carbohydrate metabolism disorders (including in the development of type 2 diabetes mellitus), lipid metabolism disorders, as well as in the pathogenesis of diseases of the cardiovascular system are considered separately. An important aspect contributing to the occurrence and progression of metabolic changes is also considered to be the invasion of fungi of the genus Candida, when an inflammatory process develops in the conditions of intestinal candidiasis dysbiosis and the process of lipid peroxidation is activated.

Author Biographies

Yury P Uspenskiy, Saint-Petersburg State Pediatric Medical University; First Saint-Petersburg State Medical University named after academician I.P. Pavlov 194100, Saint-Рetersburg; 197022, Saint-Petersburg
Litovskaya str., 2; ul. Leo Tolstoy, 6-8
Irina A Gorbacheva, First Saint-Petersburg State Medical University named after academician I.P. Pavlov 197022, Saint-Petersburg
ul. Leo Tolstoy, 6-8
Yulia A Fominykh, Saint-Petersburg State Pediatric Medical University; First Saint-Petersburg State Medical University named after academician I.P. Pavlov 194100, Saint-Рetersburg; 197022, Saint-Petersburg
Litovskaya str., 2; ul. Leo Tolstoy, 6-8
Natalia V Baryshnikova, First Saint-Petersburg State Medical University named after academician I.P. Pavlov; Institute for Experimental Medicine 197022, Saint-Petersburg; 197376, Saint-Petersburg
ul. Leo Tolstoy, 6-8; st. Academician Pavlova, 12; MD, PhD, Associate Professor of Internal Diseases Department of Stomatological Faculty
Mikhail A Shevyakov, North-Western State Medical University named after I.I. Mechnikov 191015, Saint-Petersburg; 195067, Saint-Petersburg
ul. Kirochnaya, 41.; Piskarevsky pr., d. 47
Published
2022-01-26
How to Cite
Uspenskiy, Y. P., Gorbacheva, I. A., Fominykh, Y. A., Baryshnikova, N. V., & Shevyakov, M. A. (2022). THE ROLE OF HELICOBACTER PYLORI INFECTION AND CANDIDA SPP. IN THE PATHOGENESIS OF METABOLIC SYNDROME. University Therapeutic Journal, 3(3), 35-46. Retrieved from https://ojs3.gpmu.org/index.php/Un-ther-journal/article/view/3834
Issue
Vol 3 No 3 (2021)
Section
Статьи