ADIPOSE TISSUE, LIPID METABOLISM AND IMMUNE RESPONSE

Abstract

The increase in the number of overweight and obese people observed in recent decades has led to in depth studies of the pathogenesis of this condition. It was found that obesity is accompanied by the formation of a low intensity inflammatory process as a result of an increase in the synthesis of a number of pro inflammatory mediators. Experimental data have shown that some of these mediators can have a powerful immunomodulatory effect, leading to the development of autoimmune pathology. In this article there isdiscussed the role of key participants of lipid metabolism in the formation of immune responses.