Lipid status, microbiota and bile acids: clinical and pathogenetic relationships

  • Yury P Uspenskiy Saint-Petersburg State Pediatric Medical University; First Saint-Petersburg State Medical University named after Academician I.P. Pavlov 194100, Saint-Рetersburg; 197022, Saint-Рetersburg
  • Yuliya A Fominykh Saint-Petersburg State Pediatric Medical University; First Saint-Petersburg State Medical University named after Academician I.P. Pavlov 194100, Saint-Рetersburg; 197022, Saint-Рetersburg
  • Kyamalya N Nadzhafova Saint-Petersburg State Pediatric Medical University 194100, Saint-Рetersburg
Keywords: intestinal microbiota, cholesterol, lipoproteins, bile acids

Abstract

The intestinal microbiota is a separate unique extracorporeal organ that performs many functions in the human organism. Our metabolism is inseparably linked to the activity of representatives of the gut microbiota. Recently, much attention has been paid to the study of the role of normal microbiota in lipid metabolism, as well as to the study of the influence of microbiota disorders on the formation and progression of disorders of lipid metabolism. The article presents current literature data covering this topic. Researches data are also presented that demonstrate the relationship between the blood lipid profile, the characteristics of the microbial landscape of the intestine, and the effect of probiotic strains on lipid metabolism.

Author Biographies

Yury P Uspenskiy, Saint-Petersburg State Pediatric Medical University; First Saint-Petersburg State Medical University named after Academician I.P. Pavlov 194100, Saint-Рetersburg; 197022, Saint-Рetersburg
Litovskaya str., 2; ul. Leo Tolstoy, 6-8
Yuliya A Fominykh, Saint-Petersburg State Pediatric Medical University; First Saint-Petersburg State Medical University named after Academician I.P. Pavlov 194100, Saint-Рetersburg; 197022, Saint-Рetersburg
Litovskaya str., 2; ul. Leo Tolstoy, 6-8
Kyamalya N Nadzhafova, Saint-Petersburg State Pediatric Medical University 194100, Saint-Рetersburg
Litovskaya str., 2; Assistant of Department of Faculty Therapy named after Professor V.A. Waldman.
Published
2022-05-11
How to Cite
Uspenskiy, Y. P., Fominykh, Y. A., & Nadzhafova, K. N. (2022). Lipid status, microbiota and bile acids: clinical and pathogenetic relationships. University Therapeutic Journal, 4(2), 4-13. Retrieved from https://ojs3.gpmu.org/index.php/Un-ther-journal/article/view/4054
Section
Статьи