DUODENOGASTRAL REFLUX AND CHOLELITHIASIS: PATHOGENETIC, CLINICAL AND MORPHOLOGICAL RELATIONSHIPS

  • Ruslan A Nasyrov Saint Petersburg State Pediatric Medical University Saint Petersburg, Russian Federation, 194100
  • Yulia A Fominykh Saint Petersburg State Pediatric Medical University; First Saint Petersburg State Medical University named after acad. I.P. Pavlova Saint Petersburg, Russian Federation, 194100; Saint Рetersburg, Russian Federation, 197022
  • Olga A Kizimova Saint Petersburg State Pediatric Medical University Saint Petersburg, Russian Federation, 194100
  • Alexandr B Belevitin City Consultative and Diagnostic Center No. 1 Saint Рetersburg, Russian Federation, 194354
Keywords: cholelithiasis, cholecystectomy, duodenogastric reflux, biliary gastritis, chemical gastritis, bacterial overgrowth syndrome, ursodeoxycholic acid, H pylori

Abstract

This article discusses in detail the concept of duodenogastric reflux, epidemiological data and pathogenetic aspects of this condition, including the role of changes in neurohumoral regulation, cell adhesion molecules, and the influence of Helicobacter pylori. The data on the components of duodenal refluxate, as well as their features of their effect on the gastric mucosa are presented. In addition, the article describes the algorithms for diagnosing chemical gastritis, the features of histopathological changes in chemical gastritis, the use of calculated indices in histological examination, and possible approaches to therapy.

Author Biographies

Ruslan A Nasyrov, Saint Petersburg State Pediatric Medical University Saint Petersburg, Russian Federation, 194100
Lithuania 2
Yulia A Fominykh, Saint Petersburg State Pediatric Medical University; First Saint Petersburg State Medical University named after acad. I.P. Pavlova Saint Petersburg, Russian Federation, 194100; Saint Рetersburg, Russian Federation, 197022
Lithuania 2; Leo Tolstoy str., 6-8
Olga A Kizimova, Saint Petersburg State Pediatric Medical University Saint Petersburg, Russian Federation, 194100
Lithuania 2; Assistant of the Department of Faculty Therapy named after prof. V.A. Waldman.
Alexandr B Belevitin, City Consultative and Diagnostic Center No. 1 Saint Рetersburg, Russian Federation, 194354
Siqueiros str., 10, letter A
Published
2023-03-01
How to Cite
Nasyrov, R. A., Fominykh, Y. A., Kizimova, O. A., & Belevitin, A. B. (2023). DUODENOGASTRAL REFLUX AND CHOLELITHIASIS: PATHOGENETIC, CLINICAL AND MORPHOLOGICAL RELATIONSHIPS. University Therapeutic Journal, 5(1), 36-52. Retrieved from https://ojs3.gpmu.org/index.php/Un-ther-journal/article/view/5542
Issue
Vol 5 No 1 (2023)
Section
Статьи