CLINICAL CASE OF DIPHYLLOBOTHRIOSIS

  • P.A. Aleksandrov SPIVMiR LLC, O-Tri Medical Center. Shpalernaya str., 34B, Saint-Petersburg, Russian Federation, 191123
  • N.V. Lavrov Saint Petersburg State Pediatric Medical University. Lithuania 2, Saint Petersburg, Russian Federation, 194100
  • A.R. Iskalieva Saint Petersburg State Pediatric Medical University. Lithuania 2, Saint Petersburg, Russian Federation, 194100
Keywords: children, diphyllobothriasis, epidemiological history, eosinophilia, Praziquantel, clinical case

Abstract

Diphyllobothriasis is one of the most common helminthiases in the Northern Hemisphere and in particular the Russian Federation (from 10 to 180 per 100 thousand population). Among the sick, adults and adolescents predominate, but cases of infection of young children have recently become more frequent. This publication presents a clinical case of diphyllobothriasis in a 3.5-year-old child, unrecognized at the primary stage of medical care. The described clinical case is an example of the fact that insufficient history taking and underestimation of general laboratory data can lead to delayed diagnosis and late initiation of antiparasitic therapy. There is also insufficient scientific evidence regarding the selection of a therapeutic dose of Praziquantel for children under 4 years of age. The purpose of the described case is to draw the attention of physicians (primary care and not only) to the thoroughness of taking an anamnesis (including epidemiological) and to the clinical interpretation of laboratory data in accordance with the existing clinical and epidemiological situation, to assist physicians in the treatment profile in selecting an adequate dose of Praziquantel in case of treatment of children under 4 years of age.

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Ncube M.V., Kabuyaya M., Chimbari M.J. Patient journey and resources mapping to implement a praziquantel mass drug administration program for children aged 5 years and below in resource-limited settings. 2022; 11(1): 227. DOI: 10.1186/s13643-022-02087-z.

Scholz T., Garcia H.H., Kuchta R., Wicht B. Update on the human broad tapeworm (genus diphyllobothrium), including clinical relevance. 2009; (1): 146–60. DOI: 10.1128/CMR.00033-08.

Zwang J., Olliaro P. Efficacy and safety of praziquantel 40 mg/kg in preschool-aged and school-aged children: a meta-analysis. 2017; 10(1): 47. DOI: 10.1186/s13071-016-1958-7.

Stothard J.R., Sousa-Figueiredo J.C, Betson M. et al. Closing the praziquantel treatment gap: new steps in epidemiological monitoring and control of schistosomiasis in African infants and preschool-aged children. 2011; (12): 1593–606. DOI: 10.1017/S0031182011001235.

Published
2023-12-28
How to Cite
Aleksandrov, P., Lavrov, N., & Iskalieva, A. (2023). CLINICAL CASE OF DIPHYLLOBOTHRIOSIS. University Therapeutic Journal, 5(3), 137-143. https://doi.org/10.56871/UTJ.2023.96.57.014
Section
Статьи