APPLICATION OF LOW-TEMPERATURE CORONA DISCHARGE AIR PLASMA AND FREQUENCY-MODULATED ELECTRIC FIELD SIGNAL IN WOUND TREATMENT

Abstract

An experimental study was carried out to evaluate the effectiveness of the effect of low temperature air plasma in the treatment of full thickness skin wounds in small laboratory animals. In the course of the work, full thickness skin wounds were modeled in 132 outbred rats of both sexes. A low temperature corona discharge plasma was used with an exposure time of about 15-30 seconds. Evaluation of the results of the impact of the physical method of treating wounds was estimated at 2, 7, 14, 20 days. Also, a comparative characteristic was carried out with the control group, in which the wounds were treated with iodopyrone solution, levomethyl ointment, as well as the use of a frequency modulated electric field signal and damage without treatment. The analysis revealed a pronounced positive effect of plasma on the severity of the wound process. Accelerated epithelialization of wounds was noted in comparison with the control group. The use of a new method of physical impact on wounds using low temperature air plasma and a frequency modulated electric field signal allows improving the processes of cleansing and regenerating tissues in the wound, which leads to accelerated healing. This method can be further used in medical practice to treat patients with both acute and chronic wounds.