TRENDS IN THE DEVELOPMENT OF METHODS FOR PREDICTING THE OUTCOME OF BURN DISEASE

  • Evgeniy V Zinoviev Saint-Petersburg I.I. Dzhanelidze Research Institute of Emergency Medicine; Saint-Petersburg State Pediatric Medical University 192242, Saint-Рetersburg; 194100, Saint-Рetersburg
  • Denis V Kostyakov Saint-Petersburg I.I. Dzhanelidze Research Institute of Emergency Medicine; Saint-Petersburg State University 192242, Saint-Рetersburg; 199034, Saint-Petersburg
  • Oleg O Zavorotniy Saint-Petersburg I.I. Dzhanelidze Research Institute of Emergency Medicine; Saint-Petersburg State University 192242, Saint-Рetersburg; 199034, Saint-Petersburg
  • Alexander V Semiglazov Saint-Petersburg I.I. Dzhanelidze Research Institute of Emergency Medicine 192242, Saint-Рetersburg
  • Tamara Z Gogohiya Saint-Petersburg I.I. Dzhanelidze Research Institute of Emergency Medicine 192242, Saint-Рetersburg
  • Diana H Halipaeva Saint-Petersburg I.I. Dzhanelidze Research Institute of Emergency Medicine 192242, Saint-Рetersburg
Keywords: lethal outcome, logistic regression, burns, burn disease, prediction

Abstract

The paper provides a historical review of methods for predicting the likelihood of death in patients with severe burn injury. The main criteria for making a forecast for a long time were indicators of age and area of the burn. Due to the simplicity of calculations and relatively satisfactory results, methods such as the Baux rule and the Frank index are still used in the daily practice of combustiologists. However, these methods do not take into account the main links in the pathogenesis of burn disease, and therefore the search for a way to predict a lethal outcome continues. The use of the SOFA, APACHE II, III, IV, SAPS scales for assessing vital functions in severely burned patients makes it possible to perform a relative prognosis based on an assessment of the general condition of patients without taking into account the peculiarities of the course of burn injury. It is shown that the use of selected informative indicators of laboratory and instrumental diagnostics, together with statistical analysis, logistic regression methods, will allow achieving high results in predicting mortality, and will also lead to an individual correction of the qualitative and quantitative composition of intensive care and the choice of the timing of early surgical treatment for each a patient with severe burn injury.

Author Biographies

Evgeniy V Zinoviev, Saint-Petersburg I.I. Dzhanelidze Research Institute of Emergency Medicine; Saint-Petersburg State Pediatric Medical University 192242, Saint-Рetersburg; 194100, Saint-Рetersburg
Budapest str., 3, litas. A; Litovskaya str., 2
Denis V Kostyakov, Saint-Petersburg I.I. Dzhanelidze Research Institute of Emergency Medicine; Saint-Petersburg State University 192242, Saint-Рetersburg; 199034, Saint-Petersburg
Budapest str., 3, litas. A; Faculty of Medicine.; Universitetskaya nab., 7-9
Oleg O Zavorotniy, Saint-Petersburg I.I. Dzhanelidze Research Institute of Emergency Medicine; Saint-Petersburg State University 192242, Saint-Рetersburg; 199034, Saint-Petersburg
Budapest str., 3, litas. A; Faculty of Medicine.; Universitetskaya nab., 7-9; Assistant of the Department of General Surgery
Alexander V Semiglazov, Saint-Petersburg I.I. Dzhanelidze Research Institute of Emergency Medicine 192242, Saint-Рetersburg
Budapest str., 3, litas. A
Tamara Z Gogohiya, Saint-Petersburg I.I. Dzhanelidze Research Institute of Emergency Medicine 192242, Saint-Рetersburg
Budapest str., 3, litas. A
Diana H Halipaeva, Saint-Petersburg I.I. Dzhanelidze Research Institute of Emergency Medicine 192242, Saint-Рetersburg
Budapest str., 3, litas. A
Published
2022-04-28
How to Cite
Zinoviev, E. V., Kostyakov, D. V., Zavorotniy, O. O., Semiglazov, A. V., Gogohiya, T. Z., & Halipaeva, D. H. (2022). TRENDS IN THE DEVELOPMENT OF METHODS FOR PREDICTING THE OUTCOME OF BURN DISEASE. Russian Biomedical Research, 7(1), 38-43. Retrieved from https://ojs3.gpmu.org/index.php/biomedical-research/article/view/4050
Section
Статьи