Assessment of the state of the immune system after endoprosthesis of mammary glands in aesthetic surgery

Abstract

The article is devoted to the study of the effect of mammary glands endoprosthesis with silicone implants on the state of women’s immune system in the early and long term postoperative periods. Purpose - to substantiate the effect of silicone implants on the state of the immune system of women after aesthetic endoprosthesis of the mammary glands in the early and late postoperative periods. Material and methods The study involved 70 women aged between 21 to 45 years, without concomitant pathology of organs and systems, for whom was planned to perform aesthetic endoprosthesis of the mammary glands with silicone implants. Clinical and laboratory diagnostics of blood tests were performed for all the patients before surgery, as well as the day after surgery, 6 months after and a year later. To determine the effect of the endoprosthesis of mammary glands with silicone implants on the state of the immune system of the women in the early and late postoperative periods, we studied the cellular and humoral components of the immune system. An increase in blood counts (leukocytes, lymphocytes, ESR) in the early postoperative period after endoprosthesis of the mammary glands reflects the presence of an acute inflammatory reaction in women, which can be caused not only by surgical trauma. An increase in the content of eosinophils, CRP, an increase in cellular and humoral immunity (T helpers, B lymphocytes, allergen specific IgE, IgG antibodies in the blood serum) in the early postoperative period and up to 6 months presumably indicates the development of immunological disorders in the form of the development of allergies to installed and long term silicone implants in women. However, within 1 year after the operation, laboratory blood counts are within the acceptable range. Conclusion The study of the immune system of women after endoprosthesis of mammary glands with silicone implants makes it possible to conclude that in the early postoperative period and during the first year after surgery, it is possible to develop a hypersensitive immune response to installed and long term implants in the patient’s body; however, the state of the immune system normalizes by the year after the operation, which is confirmed by clinical and laboratory research methods.