Structural and functional basis of absorption in an intestinal villus

  • N.R. Karelina Saint Petersburg State Pediatric Medical Universit 2 Litovskaya st., Saint Petersburg, 194100, Russia
  • I.D. Dimov Saint Petersburg State Pediatric Medical Universit 2 Litovskaya st., Saint Petersburg, 194100, Russia
  • K.I. Pelikh Saint Petersburg State Pediatric Medical Universit 2 Litovskaya st., Saint Petersburg, 194100, Russia
  • G.V. Beznusenko Institute of Molecular Oncology Electron Microscopy Lab, 16 Via Adamello, Milano, 20139, Italy
  • I.S. Sesorova Ivanovo State Medical Academy 8 Sheremetevskij prospekt, Ivanovo, Ivanovo Oblast, 153012, Russia
  • A.A. Mironov Institute of Molecular Oncology Electron Microscopy Lab, 16 Via Adamello, Milano, 20139, Italy
Keywords: intestinal villus, interstitial space, hematolymphatic transfer, lymphatic and blood microvessels

Abstract

Predicting possible disturbances of functional parameters of tissue under strain is one of the major goals of functional anatomy. It is of particular interest for comprehension of vital functions’ development like absorption of nutrients in the intestine. In spite of multitudinous publications describing results of morphological studies of intestinal villus, these data are mostly fragmentary and lack complex approach. The present pioneer work is devoted to histophysiology of absorption in the intestinal villus as a model of interaction of blood microvessels with lymphatic ones, all of them intimately associated with transepitelial and interstitial metabolism. Lymphatic capillaries of the intestinal villus have been demonstrated during postnatal ontogenesis to stop olaying the part of main drainage system exchanging it for forming the oncotic pressure gradient which determines hemato-interstitial-lymphatic transport of intestinal villus in adult animals. Thus, studying structural and functional basis of intestinal absorption in the aforementioned aspect is of general biological and fundamental interest.

Published
2020-05-14
How to Cite
Karelina, N., Dimov, I., Pelikh, K., Beznusenko, G., Sesorova, I., & Mironov, A. (2020). Structural and functional basis of absorption in an intestinal villus. Russian Biomedical Research, 2(2), 34-43. Retrieved from https://ojs3.gpmu.org/index.php/biomedical-research/article/view/543
Section
Статьи