STENTING OF THE ABDOMINAL AORTA IN RABBITS

Abstract

Before starting clinical trials of stents, the stage of testing them on animals is mandatory. It is rabbits that are best suited for these purposes, since their arteries are similar to the human reaction of the vascular wall to the stent. Installation of arterial implants in the abdominal aorta of a rabbit with access to vessels through the carotid artery is an inexpensive and convenient experimental model in vivo for preclinical testing of endovascular implants, in particular coronary stents, to consider the impact of new models. The first experiments on rabbits in the field of X-ray surgery of blood vessels and the heart were already at the beginning of the 20th century. Surgical intervention techniques do not require specialized instruments: standard medical devices for endovascular interventions (introducers, conductors, inflators, diagnostic catheters) are used.