PROBIOTICS IN RHEUMATIC DISEASES: A SYSTEMATIC REVIEW
Abstract
Probiotic therapy (PB) has been used in several gastrointestinal disorders. Some studies evaluated PB in rheumatic diseases. However, there is no systematic review on this subject. Objectives. To perform a systematic review of the literature regarding the clinical, therapeutic, and outcome characteristics of patients with rheumatic diseases treated with PB. Methodology. A systematic review of “rheumatic diseases” and “probiotics” was done. The following databases were used: PubMed/MEDLINE, LILACS, SciELO, Scopus, RISC, Web of Science, and Cochrane, dating from 1966 to January 2023. No limitation in languages was applied. Although not in all, but in majority of clinical and experimental studies reviewed some favorable effects of probiotics in several rheumatic diseases were documented. Most probably, probiotic treatment is a useful and safe complementary therapy for rheumatic patients.
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