Promising methods for substitution of skull bone defects

  • D.E. Alekseev S. M. Kirov Military Medical Academy, 194044, St. Petersburg, Academician Lebedev str., lit. F
  • D.V. Svistov S. M. Kirov Military Medical Academy, 194044, St. Petersburg, Academician Lebedev str., lit. F
  • A.E. Korovin S. M. Kirov Military Medical Academy, 194044, St. Petersburg, Academician Lebedev str., lit. F
  • L.A. Rumyantsev S. M. Kirov Military Medical Academy, 194044, St. Petersburg, Academician Lebedev str., lit. F
  • I.K. Kramcheninov 3rd scientific company of the Military-innovative technopolis «ERA», 143405, Russia, Moscow region, Krasnogorsk military town Pavshina 33/1 incl. 26302
Keywords: cellular technology, osteogenesis, stem cells, bone tissue engineering, graft

Abstract

The article considers the modern methods of treatment of injuries of the skull bones in wartime and peacetime. On the basis of literary analysis shows the clinical application of cell technologies in tissue engineering. Discusses the positive and negative aspects of the use of implants of different nature. Preferred carrier material bioorganic origin stimulating osteogenesis. Development of new biotechnological methods in transplantation is impossible without the active participation of experts of diverse profiles. Promising to date are the technology of gene-activated bone implants with the help of genetic engineering, which provides the necessary vital functions of populated stem cells. The successes of domestic regenerative medicine in the field of transplantation in the near future will allow to significantly improve the quality of life of victims in the early stages of rehabilitation. 

Published
2019-03-13
How to Cite
Alekseev, D., Svistov, D., Korovin, A., Rumyantsev, L., & Kramcheninov, I. (2019). Promising methods for substitution of skull bone defects. Russian Biomedical Research, 3(1), 18-24. Retrieved from https://ojs3.gpmu.org/index.php/biomedical-research/article/view/71
Section
Статьи