ENDOTHELIAL DYSFUNCTION IN OBESE CHILDREN

Abstract

This review demonstrates data related to the function of endothelium in normal physiological state and in cases of obesity. The new clinical methods of endothelium status assessment in large and small blood vessels are presented. Special focus is placed on the observation that the endothelial dysfunction and vessel rigidity connected therewith are the first phases of the development of atherosclerotic changes and manifest increasing risk of development of cardiovascular pathologies. Extra body mass and obesity in infancy are associated with progressive endothelial dysfunction and formation of total metabolic syndrome.