Antibiotic resistance of enterobacteriae strains isolated from blood

Abstract

Klebsiella pneumoniae (76.0%) and Escherichia coli (22.6%) strains prevailed among enterobacteria isolated from the blood of patients from the multidisciplinary hospital in St. Petersburg. Detection the susceptibility of enterobacteria to 9 antimicrobial agents revealed a high proportion of antibiotic resistant cultures with a predominance of multiresistant (MDR) strains (88.4%). The proportion of insensitive to carbapenems isolates was high (38.4%), especially in K. pneumoniae (46.8%). A third (33.6%) isolates of enterobacteria, including 46.4% of K. pneumoniae strains and 9.1% of E. coli cultures, were resistant to all studied antimicrobial agents. Almost half of such cultures (46.9%) were isolated in one of the departments of the hospital. Spread of extreme resistant K. pneumoniae strains and appearance of same E. coli cultures, is a dangerous sign of the significant decrease in carbapenems and other antimicrobial agents efficacy towards infections, caused by such strains and confirm the necessity of antimicrobial resistance monitoring in hospitals strains.