Biodegradable material for substitution of bone tissue

  • Виктория Андреевна Набока Saint-Petersburg State Institute of Technology 190013, St. Petersburg
  • Алексей Александрович Климентьев Saint-Petersburg State Institute of Technology 190013, St. Petersburg
  • Рафаиль Фаилевич Габидуллин Federal Scientific Center of Rehabilitation of the Disabled named after G A Albrecht of the Ministry of Labour and Social Protection of the Russian Federation 195067, St. Petersburg
Keywords: silk fibroin, hydroxyapatite, biodegradable material, bone tissue regeneration

Abstract

The biodegradable bone replacement material was derived from three main components: silk fibroin Bombyx mori, calcium phosphates, and casein. Regenerative properties of the matrices were evaluated in experiments on rats during implantation into bone defects. According to x ray tomography, the use of biodegradable material provided the restoration of the integrity of the bone in a faster time. Analysis of the histograms obtained from the defect area also showed more pronounced regeneration processes when filling bone defects with biocompatible material compared to the control group.

Author Biographies

Виктория Андреевна Набока, Saint-Petersburg State Institute of Technology 190013, St. Petersburg
Moskovsky pr., 26
Алексей Александрович Климентьев, Saint-Petersburg State Institute of Technology 190013, St. Petersburg
Moskovsky pr., 26
Рафаиль Фаилевич Габидуллин, Federal Scientific Center of Rehabilitation of the Disabled named after G A Albrecht of the Ministry of Labour and Social Protection of the Russian Federation 195067, St. Petersburg
ul. Bestuzhevskaya, 50; resident physician
Published
2020-06-02
How to Cite
Набока, В. А., Климентьев, А. А., & Габидуллин, Р. Ф. (2020). Biodegradable material for substitution of bone tissue. Medicine: Theory and Practice, 4(3), 209-215. Retrieved from https://ojs3.gpmu.org/index.php/med-theory-and-practice/article/view/2327
Issue
Vol 4 No 3 (2019)
Section
Статьи