Peculiarities of cardiovascular risk factors and clinical course of myocardial infarction in men under 60 years with bronchial asthma

Abstract

Background. The study of comorbidity for the therapy personification is one of the methods for improving the myocardial infarction (MI) prevention of recent years. The data on the MI clinical features in young and middle aged men suffering from bronchial asthma (BA) are few and contradictory. Purposes and tasks. To assess the frequency of cardiovascular diseases risk factors, the course of MI, and hemodynamic changes in men under 60 years old to improve prevention. Materials and methods. The study included men from 19 to 60 years old with type I IM diagnosed and treated according to the standards at the time of hospitalization. Patients were divided into two age comparable groups: I - the study group, with BA - 6 patients; II - without BA - 424 people as a control group. A comparative analysis of the frequency of observation of primary and secondary cardiovascular diseases risk factors, the course of MI, and hemodynamic changes. The results. The study showed that the distinctive MI risk factors in men with BA were a history of chronic heart failure (HF), a hereditary burden of coronary heart disease, and atherogenic dyslipidemia. The patients with BA had atypical variants of the MI course with predominance of disease complications such as cardiac arrhythmias and cardiac asthma. Moreover, the patients with BA had more pronounced hemodynamic disturbances both in acute and subacute periods of MI. Conclusions. The men with BA and MI should stay under medical supervision to identify and treat chronic HF and should be further examined to exclude non atherosclerotic variants of coronary artery disease or embolism.