FEATURES OF REACTION IN VITRO TESTS AND SKIN TESTS WITH TUBERCULAR ALLERGENS DEPENDING ON VARIANTS OF THE TUBERCULOSIS INFECTION IN CHILDREN

  • Марина Эдуардовна Лозовская Saint-Petersburg State Pediatric Medical University, 194100, Saint-Petersburg, Litovskaya str., 2
  • Ольга Петровна Гурина Saint-Petersburg State Pediatric Medical University, 194100, Saint-Petersburg, Litovskaya str., 2
  • Елена Александровна Дементьева Saint-Petersburg State Pediatric Medical University, 194100, Saint-Petersburg, Litovskaya str., 2
  • Е Б Васильева Saint-Petersburg State Pediatric Medical University, 194100, Saint-Petersburg, Litovskaya str., 2
  • Л В Клочкова Saint-Petersburg State Pediatric Medical University, 194100, Saint-Petersburg, Litovskaya str., 2
  • Н Д Шибакова Saint-Petersburg State Pediatric Medical University, 194100, Saint-Petersburg, Litovskaya str., 2
  • В В Белушков Saint-Petersburg State Pediatric Medical University, 194100, Saint-Petersburg, Litovskaya str., 2
Keywords: QuantiFERON, children, tuberculosis, Diaskintest, Tubinferon

Abstract

Тhe results of three tests on the basis of CFP-10 and ESAT-6 antigens: intracutaneous Diaskintest
and two in vitro tests QuantiFERON and Tubinferon were studied in 63 children of age from 0 to 15 years.
Among the examined children 8 patients those not infected with tuberculous mycobacteria, 15 patients are
infected from last years, 14 patients are in the early period of primary tuberculosis infection, 26 children
ill with tuberculosis. It is established that at high rate of coincidence of results of all three test (69,8%) in
particular situations they can react differently, providing thereby additional information. At acceptance
of QuantiFERON for the reference test at a tuberculosis infection, Tubinferon’s sensitivity was 64,7%,
specificity 75,9%.

Published
2019-03-14
How to Cite
Лозовская, М. Э., Гурина, О. П., Дементьева, Е. А., Васильева, Е. Б., Клочкова, Л. В., Шибакова, Н. Д., & Белушков, В. В. (2019). FEATURES OF REACTION IN VITRO TESTS AND SKIN TESTS WITH TUBERCULAR ALLERGENS DEPENDING ON VARIANTS OF THE TUBERCULOSIS INFECTION IN CHILDREN. Medicine: Theory and Practice, 3(3 приложен), 13-18. Retrieved from https://ojs3.gpmu.org/index.php/med-theory-and-practice/article/view/337
Issue
Vol 3 No 3 приложен (2018)
Section
Статьи