RECENT BIOMARKERS OF RENAL INJURE

Abstract

Acute kidney injury is a broader concept than acute renal failure, as even minor changes in renal function have a significant effect on the results of treatment. The emergence of AKI increases the risk of mortality, length of stay and cost of treatment. In the past few years increasing attention attended to the possibility of using biomarkers in the diagnosis of acute kidney injury because of disadvantages of the traditional parameters such as serum creatinine and urea, diuresis measurement, which on the one hand depends on a number of extrarenal factors, on the other — they change occurs in the later, irreversiblestages of renal tissue damage. The development of kidney amyloidosis also in the early stages does not have a clear clinical equivalent and can be detected only with the help of special biomarkers. The purpose of this literature review — analyze the possibility of using a number of markers in the early diagnosis of different types of acute kidney injury.