Cardiovascular risk factors peculiarities of in men under 60 years old with urinary disorders in myocardial infarction

Abstract

Background. Urological pathology can significantly worsen the myocardial infarction course. Most of the known data about the combined course of the myocardial infarction precursors have been obtained for elderly and senile patients. Purposes and tasks. To evaluate the features of the of cardiovascular risk factors structure in men under 60 years old with myocardial infarction complicated by urinary disorders to improve prevention and outcomes. Materials and methods. The study included men 19-60 years old with type I myocardial infarction. The patients were divided into two age comparable groups: I - study group, with urinary disorders - 22 patients; II - control, without it - 644 patients. A comparative analysis of the main and additional cardiovascular risk factors frequency, analysis of their influence on the risk of urinary disorders in myocardial infarction (ANOVA) were performed. The results. The study group differed from the control group in the greater frequency of coronary artery bypass surgery in the history (in the study group: 31.8%; in the control group: 8.4%; p=0.0002) and pacing (9.1 and 0.5%; respectively) ; p<0.0001), as well as a history of atrial fibrillation and/or flutter (27.3 and 9.2%; p=0.005), chronic cerebrovascular insufficiency (77.3 and 51.3%; p=0,02), alcohol abuse (63.6 and 25.2%; p<0.0001), frequent (four or more per year) colds (27.3 and 12.6%; p=0.04), heart rhythm and conduction disturbances at the onset of coronary artery disease (61.9 and 24.9%; p=0.0007), smoking for 20 years or more (36.4 and 16.8%; p=0.003), chronic kidney disease (46.7 and 16.2%; p=0.02), chronic foci of infection of internal organs (77.3 and 39.4%; p=0.002), urine (27.3 and 8.6%; p=0.006) and gallstone diseases (13.6 and 5.4%; p=0.006). Smoking (absolute risk: 4.4%; relative: 8.0; p=0.01), metabolic disorders (8.1%; 3.2; p=0.002, respectively), chronic kidney disease (8.1%; 4.2; p=0.002), heart rhythm and conduction disorders (7.7; 4.6%; p=0.0001), alcohol abuse (8.0%; 4.9; p<0.0001), frequent colds (6.9%; 2.5; p=0.04) and chronic foci of infection of internal organs (6.3%; 5.0; p=0,0004). Conclusions. The listed factors are characteristic for the development of urination disorders in myocardial infarction in men under 60 years of age. They should be used in the formation of high risk groups for the development of these conditions in myocardial infarction, as well as for predictive modeling.