Иммунитет и атопия. Особенности у детей

Ольга Петровна Гурина; Александр Евгеньевич Блинов; Ольга Николаевна Варламова; Елена Александровна Дементьева; Арина Александровна Степанова; Георгий Александрович Блинов

Ольга Петровна Гурина Saint-Petersburg State Pediatric Medical University. 194100, Russia, Saint-Рetersburg, Litovskaya str., 2
Александр Евгеньевич Блинов Saint-Petersburg State Pediatric Medical University. 194100, Russia, Saint-Рetersburg, Litovskaya str., 2
Ольга Николаевна Варламова Saint-Petersburg State Pediatric Medical University. 194100, Russia, Saint-Рetersburg, Litovskaya str., 2
Елена Александровна Дементьева Saint-Petersburg State Pediatric Medical University. 194100, Russia, Saint-Рetersburg, Litovskaya str., 2
Арина Александровна Степанова Saint-Petersburg State Pediatric Medical University. 194100, Russia, Saint-Рetersburg, Litovskaya str., 2
Георгий Александрович Блинов Saint-Petersburg State Pediatric Medical University. 194100, Russia, Saint-Рetersburg, Litovskaya str., 2

Keywords: immunity, atopic asthma, atopic dermatitis, autoantibodies, immunoglobulins, lymphocytes, phagocytes

Abstract

The study of the immunity and immunopathology reactions in children aged 4 months to 16 years, suffering from atopic diseases (atopic asthma — 200 children, atopic dermatitis — 66 children). Immune status was studied by immunological tests of level 1, subpopulation composition of lymphocytes — by flow cytometry, autoimmune antibodies — by enzyme immunoassay. Heterogeneity of immunity disorders, development of autoimmune process (production of autoantibodies to tissue antigens) are shown. The need for the use of complex immunocorrection aimed at the normalization of almost all parts of the immune system in the treatment of atopic diseases was noted. Immunorehabilitation of children with atopic asthma and atopic dermatitis should be carried out taking into account the presence and activity of autoimmune inflammation

Immunity and atopy. Especiall y in children

Abstract