Dependence of newborn homeostasis on the quality composition of basic infusion therapy

Abstract

The data of a prospective comparison of glucose, urea, potassium and sodium serum concentrations, urine output and body weight dynamics depending on the qualitative composition of the basic infusion therapy of newborns demonstrated the negative effect of an isotonic sodium chloride and salt-free glucose fluids on serum sodium concentration and osmolarity. The correlation between glucose and sodium concentrations was characterized. The relationship of serum hypo- or hyperosmolarity with intraventricular hemorrhage and cerebral infarction was shown in newborns. Isotonic sodium chloride and salt-free glucose fluids should be excluded of the long-term infusion therapy in newborns.