CELLULAR AND HUMORAL IMMUNITY IN PATIENTS WITH MULTIFOCAL ATHEROSCLEROSIS

Abstract

67 patients were observed: 52 males and 15 females with absolutely confirmed diagnosis of ischemic heart disease (IHD), angina pectoris of I-IV functional class (CCS). All of patients were comparable by age. All of patients were performed coronaroangiography, angiography of various vascular areas: brachiocephalic arteries, abdominal part of aorta, renal arteries, main arteries of low extremities. Also immunological indices were determined such as myocardial antigen, anti-myocardial antibodies, circulating immune complexes (CIC), IgA, IgM, IgG. The data indicate the correlation of the number of affected areas with the blood level of CIC. It was proved by the method of logistical regression. In patients with multifocal atherosclerosis the higher blood levels of IgG and IgM also were found.