IMPLEMENTATION OF POLARIZED LIGHT TECHNICUES TO DIAGNOSE AND PREVENT IODINE DEFICIENCY DISEASES IN CHILDREN

Abstract

The conducted research is aimed at developing a method for prenosological rapid diagnosis of diseases affecting children using polarized light (using the example of iodine deficiency states (IDS)). The study involved 46 children aged 7-10 years vacationing in the children’s sanatorium. The method was developed in order to assess the kinetic activity of the buccal epithelium (CABE) with the use of polarized light to diagnose IDS. For comparison, the degree of risk of IDS was simultaneously determined by the diagnostic coefficient (DC) of the prognostic screening table. According to the authors’ method of rapid diagnosis of IDS with the use of blue polarized light and the determination of the CABE indicator, all children who participated in the study were divided into three groups according to the CABE value: the first - 9 people, CABE indicators are high - 7% or more above the baseline level; the second - 27 people, CABE indicators are up to 6.9%; the third - 10 people, where CABE indicators did not change. According to the results of the analysis of the indicators of the prognostic screening table determined by us, the children were distributed as follows with respect to IDS: the risk of occurrence of IDS is high -16 people, the risk of occurrence of IDS is average - 24 people and the risk of occurrence of IDS is low - 6 people. The differences in quantitative indicators (%) in children’s groups, established during the diagnosis of IDS in two ways, are unreliable, the technology to obtain indicators for the diagnosis of IDS is different. The prenosological diagnosis of IDS, carried out by the authors’ method, is objective and takes both less time and less financial costs. For the first time in the diagnosis of IDS, a non -invasive, objective, economical method is proposed, where the presence of IDS is determined by the value of the CABE using polarized blue light. The method also assumes the possibility of evaluating the effectiveness of the ongoing therapy of the disease.