Personalized therapy with use of screening drugs in pediatrics

Currently, personalized medicine is one of the most promising areas of medicine XXI century. We review the data on the use of screening drugs in vitro by its effect on the thiol-disulfide ratio (TDR) of blood for the personalized treatment of chronic hepatitis C, herpes and human papillomavirus infection, chronic bronchitis, repeated giardiasis in children and adults, as well as personalized immunotherapy of frequently ill children. It is concluded that this method can be used to personalize the antibacterial, antiviral, antiprotozoal and immunotherapy in children in order to increase its efficiency, to overcome resistance to antibiotic, antiviral, antiprotozoal and immune drugs, search for the best medications, their dosages and combinations, reducing the incidence of side effects and cost of treatment.