PORTRAIT OF THE PHENOTYPE OF A PATIENT WITH CHRONIC HEART FAILURE INFECTED BY HUMAN IMMUNODEFICIENCY VIRUS

Abstract

Introduction. The multifactorial nature of the formation of chronic heart failure (CHF) in patients infected with HIV is not fully understood. It is known that HIV infection is influenced not only by traditional risk factors for the development of CHF, but also by other factors associated with the impact of the virus on the cardiovascular system. The purpose of the study is to analyze the features of the formation of a portrait of the phenotype of a patient with CHF infected with HIV. Materials and methods. In a large city clinical hospital in Perm, from 2019 to 2023, 240 hospitalized HIV-infected patients were examined, of which 160 people (66.7%) were diagnosed with CHF. The comparison group consisted of 160 patients with CHF who did not have HIV infection and did not have acute decompensation of CHF. Result. During the examination two groups of patients with CHF, it is possible to imagine a portrait of a patient with CHF infected with HIV. This is most often a man in his fourth decade of life, with low body weight, committed to smoking and drinking alcohol. CHF in HIV infection is accompanied by inflammatory syndrome, anemia, thrombocytopenia and even pancytopenia, thrombosis, comorbidity with chronic hepatitis C and opportunistic inflammatory diseases. Сonclusion. phenotypic profile of a patient with HIV infection and chronic heart failure is more likely to be characterised by a man in his fourth decade of life, with low body weight, systemic haematopoiesis disorders, marked inflammatory syndrome and comorbidity with with viral hepatitis C.