MORPHOLOGICAL LIVER CHANGES IN CASE OF VARIOUS ETHIOLOGY FATTY DISTROPHY

Abstract

Until nowadays there is no common opinion regarding the changes that are taking place in hepatocytes during the development of Liver Fatty Distrophy (LFD). Clinical interpretations assessment of LFD are contradictory as well as the degree of the risk factors determination and the rate of inflammation progressing and hepatocytes’ damage, and the absence of concrete LFD and metabolic steatohepatite differential criteria absence, thus dictating the necessity of the search for new diagnostic approaches and correction of these complications. In spite of considerable interest and medico social interest towards this problem the importance of LFD role for complications risk prognosis is yet unsolved. The present study reproduced and perfected various etiology LFD models: alcoholic, non alcoholic and combination. High carbohydrate and ethanol rich diet causes fast development of pathological processes in the liver. Expediency of detailed morphological scrutiny of the liver has been demonstrated side by side with anamnestic studies, laboratory testing of cytolitic and cholestatic syndrome parameters for differential diagnostics of various etiology LFD.