CLINICAL METAMORPHOSIS OF PNEUMONIA IN CHILDRENOF THE XXI CENTURY (REVIEW)

Abstract

The article reviews the publications of well known Russian and occidental pulmonologists, pediatricians, devoted to the study of current features of the clinical course of pneumonia, which remain one of the main causes of death in children in the first 5 years of life. Changes in the classic symptoms of community acquired pneumonia in children can serve as a source of diagnostic errors, ineffectiveness of treatment, and the formation of complications. The evolution of scientists views on the causes and mechanisms of the development of pneumonia is analyzed, the role of the respiratory microbiome, atypical pathogens in overcoming the bronchovascular and aerohematic defense, in changing the morpho functional state of the lung tissue, in the formation of clinical features of its lesion, as well as optimization of diagnostic programs that allow timely detection atypical pneumonia, to carry out targeted therapy.