FEATURES OF CHRONIC GASTRITIS IN ADOLESCENTS

Abstract

Introduction. Chronic gastritis occupies the first place in the structure of the pathology of the digestive organs in adolescents. The aim of the study is to establish the features of chronic gastritis in adolescence in order to improve its diagnosis and medical support for this category of patients. Materials and methods. 115 adolescents aged 11-17 years with chronic gastritis were examined. Clinical and anamnestic data, the results of laboratory, parasitological, esophagogastroduodenoscopic and morphological studies, as well as genetic typing of Hp were evaluated, during which Hp pathogenicity factors were identified (“DNA Technology test systems”, polymerase chain reaction). Results. Chronic gastritis in adolescence is represented by its Hp associated variant (92.2 %), in 55.8 % of cases there is colonization of the gastric mucosa by highly pathogenic Hp strains. In the absence of significant differences in the clinical manifestations of the disease, widespread hyperplastic inflammation of moderate or severe degree and activity with the appearance of signs of undetermined atrophy of the gastric mucosa is recorded in this group of patients. Conclusion. It is advisable to supplement the examination program of adolescents with Hp associated chronic gastritis with genetic typing of HP to identify patients infected with its highly pathogenic strains.