INTESTINAL MICROBIOME AS A REGULATOR OF DEVELOPMENT AND FUNCTIONING NERVOUS SYSTEM

Abstract

Experimental and clinical studies in recent years provide more and more evidence that the normal development and functioning of the brain is largely influenced by the symbiotic microbiota. The identification of specific disorders in the interrelations of the intestinal microflora and the nervous system has made it possible to characterize in more detail the pathogenesis of such complex pathologies as neurodegenerative diseases, depressive disorders, and childhood autism. It was found that the intestinal microbiota plays an important role in determining the stress response and behavioral phenotype of the host. Prospects for the study of the microbiota suggest fundamentally new views on strategies for the prevention and treatment of mental and psychosomatic disorders, taking into account the microbiota factor.