THE ROLE OF THE INTESTINE IN THE FORMATION OF SENSORIOR HEARING LOSS

  • Pavel V Pavlov Saint-Petersburg State Pediatric Medical University 194100, Saint-Petersburg
  • Ekaterina S Garbaruk Saint-Petersburg State Pediatric Medical University 194100, Saint-Petersburg
Keywords: sensorineural hearing loss, inner ear, cochlea, obesity, diabetes, microbiota, gut dysbiosis

Abstract

Hearing impairment is the most common sensory impairment, which is currently considered as a global problem of modern health care. It is hypothesized that inflammatory bowel disease, diabetes, obesity, and a high fat diet may correlate with sensorineural hearing loss. Some research suggests that obesity may be a factor in the development of hearing loss. The main mechanisms causing cochlear pathology in obesity and metabolic disorders may be cochlear microangiopathy, dyslipidemia, redox imbalance, and impaired insulin signaling. A significant amount of data has accumulated indicating an association between type 2 diabetes mellitus and sensorineural hearing loss. However, the nature of the pathogenetic relationship between these diseases remains unclear and poorly understood. There is no clear indication that the state of the gut microbiota directly affects the functioning of the inner ear.

Author Biographies

Pavel V Pavlov, Saint-Petersburg State Pediatric Medical University 194100, Saint-Petersburg
Litovskaya str., 2
Ekaterina S Garbaruk, Saint-Petersburg State Pediatric Medical University 194100, Saint-Petersburg
Litovskaya str., 2; PhD, Senior Researcher, Research Center of the Saint-Petersburg State Pediatric Medical University
Published
2022-12-14
How to Cite
Pavlov, P. V., & Garbaruk, E. S. (2022). THE ROLE OF THE INTESTINE IN THE FORMATION OF SENSORIOR HEARING LOSS. Children’s Medicine of the North-West, 10(4), 42-45. Retrieved from https://ojs3.gpmu.org/index.php/childmed/article/view/5490
Section
Статьи