A CLINICAL CASE OF LOWER RESPIRATORY TRACT INFECTION CAUSED BY ELIZABETHKINGIA MENINGOSEPTICA IN A CHILD WITH CEREBRAL PALSY

  • E.V. Loshkova Research Clinical Institute of Childhood of the Ministry of Health of the Moscow Region. Bolshaya Serpukhovskaya st., 62, Moscow, Russian Federation, 115093 http://orcid.org/0000-0002-3043-8674
  • A.V. Lyamin Samara State Medical University. Chapaevskaya st., 89, Samara, Russian Federation, 443099
  • G.N. Yankina Siberian State Medical University. Moskovsky tract, 2, Tomsk, Russian Federation, 634050
  • T.S. Lyulka Siberian State Medical University. Moskovsky tract, 2, Tomsk, Russian Federation, 634050
Keywords: pneumonia; cerebral palsy; children; Elizabethkingia meningoseptica; nutritional status; antibiotic resistance

Abstract

The most common cause of morbidity and mortality in patients with cerebral palsy (Cerebral Palsy, CP), including in childhood, is associated with respiratory diseases. Patients with SR are characterized by a decrease in local immunity of the upper and lower respiratory tract, increased viral incidence, progression of a bacterial infection without additional infection or an increase in the number of microbial numbers, a decrease in lung function, and infection of the respiratory tract with a microfl ora atypical for practically healthy children. SR is a disease that occurs with severe comorbid conditions, it is epilepsy, requiring constant basic therapy, accompanied by standard negative side eff ects, it is both severe gastrointestinal problems and associated severe
nutritional status disorders, and defi cient conditions that contribute to infectious process against the background of SR. A clinical observation of a patient with SR who had severe community-acquired pneumonia caused by Elizabethkingia meningoseptica, which developed while taking glucocorticosteroids, is described. The diffi culties of managing a child when prescribing empirical antimicrobial therapy and successful eradication of the pathogen with clinical and radiological recovery of the patient after the detection of Elizabethkingia meningoseptica in the bronchoalveolar lavage fl uid and the appointment of antibiotic therapy based on the results of the obtained antibiogram are described. The authors draw attention to the pathogenetic features of the implementation of respiratory and nutritional disorders in a cohort of patients with SR and the need to personalize diagnostic and therapeutic measures in each case.

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Published
2024-03-19
How to Cite
Loshkova, E., Lyamin, A., Yankina, G., & Lyulka, T. (2024). A CLINICAL CASE OF LOWER RESPIRATORY TRACT INFECTION CAUSED BY ELIZABETHKINGIA MENINGOSEPTICA IN A CHILD WITH CEREBRAL PALSY. Children’s Medicine of the North-West, 11(4), 88-98. https://doi.org/10.56871/CmN-W.2023.41.58.011
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