COLLAGENS IN THE GASTROINTESTINAL MUCOSA: PEDIATRIC ASPECTS
Abstract
The spectrum of collagen diseases of the digestive tract is diverse and is divided into three categories: collagenous gastritis, collagenous sprue (collagen enteritis) and collagenous colitis. According to N. Nyhlin et al. (2006), the total annual incidence of CC in the adult section is 4–6 cases per 100,000 people, being one of the causes of chronic diarrhea in elderly patients. It is known that in pediatric practice, the most common form is collagenous gastroenteritis, which is often the cause of severe iron defi ciency anemia, which reacts to oral iron supplements, but may recur after drug withdrawal. The disease can be considered as a new possible cause of severe iron defi ciency anemia and abdominal pain in children, therefore it is an urgent topic for randomized trials today. The literature review presents data from the analysis of scientifi c publications of compatriots and foreign colleagues related to collagen diseases in children, in order to increase awareness and alertness about the pathology.
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