ИНТЕНСИВНАЯ ТЕРАПИЯ ОСЛОЖНЕНИЙ САХАРНОГО ДИАБЕТА У ДЕТЕЙ

Yu.S. Aleksandrovich; D.O. Ivanov; K.V. Pshenisnov; D.V. Prometnoy; V.V. Kopylov; P.A. Muratov; L.V. Ditkovskaya

doi:10.56871/CmN-W.2024.40.20.008

Yu.S. Aleksandrovich Saint Petersburg State Pediatric Medical University. Lithuania 2, Saint Petersburg, Russian Federation, 194100
D.O. Ivanov Saint Petersburg State Pediatric Medical University. Lithuania 2, Saint Petersburg, Russian Federation, 194100
K.V. Pshenisnov Saint Petersburg State Pediatric Medical University. Lithuania 2, Saint Petersburg, Russian Federation, 194100 http://orcid.org/0000-0003-1113-5296
D.V. Prometnoy Russian Children’s Clinical Hospital of the «Russian National Research Medical University named after N.I. Pirogov». Leninsky pr., 117, Moscow, Russian Federation, 119571
V.V. Kopylov V.A. Almazov National Medical Research Center. Akkuratova str., 2, Saint Petersburg, Russian Federation, 197341
P.A. Muratov Children’s City Multidisciplinary Clinical Center for High Medical Technologies named after K.A. Rauhfus. Ligovsky pr., 8, Saint Petersburg, 191036
L.V. Ditkovskaya Saint Petersburg State Pediatric Medical University. Lithuania 2, Saint Petersburg, Russian Federation, 194100

DOI: https://doi.org/10.56871/CmN-W.2024.40.20.008

Keywords: type 1 diabetes mellitus, complications, children, diabetic ketoacidosis, intensive therapy

Abstract

Introduction. Complications of diabetes mellitus are one of the most common life-threatening conditions in pediatric practice. The aim of the study was to analyze modern principles of intensive therapy of diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic coma (HHC) in children. Results. The peculiarities of volemic load and insulin therapy were demonstrated, special attention was paid to prevention and correction of intracranial hypertension, treatment of cerebral edema. The necessity of prevention of sharp fl uctuations of blood plasma osmolarity, timely and step-by- step correction of water-electrolyte disorders was noted. Conclusion. The basis of successful treatment of diabetes mellitus complications in children is early diagnosis and correction of systemic hypoperfusion, prevention of cerebral ischemia and intracranial hypertension.

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INTENSIVE CARE OF COMPLICATIONS OF DIABETES MELLITUS IN CHILDREN

Abstract

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