MONITORING OF RENAL TISSUE OXYGENATION IN YOUNG CHILDREN WITH CONGENITAL HEART DISEASE IN THE PERIOPERATIVE PERIOD
Abstract
Introduction. Tissue oximetry is one of the most promising methods for assessing the efficiency of systemic perfusion in children in critical condition, which is especially true for newborns with heart defects, but it is not a routine method of diagnosing systemic hypoperfusion in neonatal intensive care units, which requires its wider implementation. The aim of the study is to demonstrate the possibilities of prolonged NIRS-monitoring of renal tissue oxygenation to determine further tactics of management of newborns with congenital heart disease. Patients and methods. Three clinical cases of prolonged noninvasive monitoring of renal oxygenation in infants with congenital heart disease accompanied by systemic hypoperfusion in the perioperative period are presented. Results. It was demonstrated that on the basis of renal tissue oxygenation indices it is possible to make an informed decision on the correction of intensive care measures and the need for emergency cardiac surgery. In some cases, NIRS-monitoring allows to avoid early intubation and invasive ventilation of lungs, which is reflected in the description of the third case. Conclusion. Noninvasive real-time bedside monitoring of tissue oxygenation is a highly eff ective method of diagnosing systemic hypoperfusion and should be more widely used in neonatal intensive care units, especially in neonates with CHD, in whom the risk of shock of various genesis is extremely high.
References
Jöbsis FF. Noninvasive, infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters. Science. 1977; 198(4323): 1264–7. DOI:10.1126/science.929199.
Kleinman C.S., Seri I. Hemodynamics and cardiology: neonatology questions and controversies. 3nd ed. Philadelphia: Elsevier; Saunders. 2015: 132–7.
Denault A., Deschamps A., Murkin J.M. A proposed algorithm for the intraoperative use of cerebral near-infrared spectroscopy. Semin Cardiothorac Vasc Anesth. 2007; 11(4): 274–81. DOI: 10.1177/1089253207311685.
Engelhardt B., Gillam-Krakauer M. Use of near-infrared spectroscopy in the management of patients in neonatal intensive care units — an example of implementation of a new technology In: Th. Theophanides (ed.). Infrared Spectroscopy — Life and Biomedical Sciences. 2012. DOI: 10.5772/37994. http:// www.intechopen.com/books/infrared-spectroscopy-life-andbiomedical-sciences/use-of-near-infrared-spectroscopy-in-themanagement-of-patients-in-neonatal-intensive-care-units-a. (Аaccess 28.12.2023).
De Backer D., Ospina-Tascon G., Salgado D. et al. Monitoring the microcirculation in the critically ill patient: current methods and future approaches. Intensive Care Med. 2010; 36(11): 1813–25. DOI: 10.1007/s00134-010-2005-3.
McCormick P.W., Stewart M., Goetting M.G. et al. Noninvasive cerebral optical spectroscopy for monitoring cerebral oxygen delivery and hemodynamics. Crit Care Med. 1991; 19(1): 89–97. DOI: 10.1097/00003246-199101000-00020.
Hogue C.W., Levine A., Hudson A., Lewis C. Clinical Applications of Near-infrared Spectroscopy Monitoring in Cardiovascular Surgery. Anesthesiology. 2021; 134(5): 784–91. DOI: 10.1097/ALN.0000000000003700.
Ikeda M., Hayashida M., Kadokura Y. et al. Associations among preoperative transthoracic echocardiography variables and cerebral near-infrared spectroscopy values at baseline before anesthesia in patients undergoing cardiac surgery: a retrospective observational study. Heart Vessels. 2023; 38(6): 839–48. DOI: 10.1007/s00380-023-02233-0.
Soenarto R.F., Hidayat J.K., Eureka O., Auerkari A.N. Can near-infrared spectroscopy (NIRS) monitoring prevent post-operative cognitive dysfunction following open- heart surgery? J Pak Med Assoc. 2021; 71(Suppl 2): S10–3.
Delpy D.T., Cope M.C., Cady E.B. et al. Cerebral monitoring in newborn infants by magnetic resonance and near infraredspectroscopy. Scand J Clin Lab Invest Suppl. 1987; 188: 9–17.
Edwards A.D., Wyatt J.S., Richardson C. et al. Cotside measurement of cerebral blood flow in ill newborn infants by near infrared spectroscopy. Lancet. 1988; 2(8614): 770–1.
Choi J. et al. Noninvasive determination of the optical properties of adult brain: near-infrared spectroscopy approach. J Biomed Opt. 2004; 9(1): 221–9.
Bailey S.M., Prakash S.S., Verma S. et al. Near-infrared spectroscopy in the medical management of infants. Curr Probl Pediatr Adolesc Health Care. 2022; 52(11): 101291. DOI: 10.1016/j.cppeds.2022.101291.
Tran N.N., Tran M., Lopez J. et al. Near-infrared spectroscopy: clinical use in high-risk neonates. Neonatal Netw. 2021; 40(2): 73–9. DOI: 10.1891/0730-0832/11-T-678.
Candan T., Candan M., Yildiz C.E. et al. Comparison of bilateral cerebral and somatic tissue oxygenation with near-infrared spectroscopy in cyanotic and acyanotic pediatric patients receiving cardiac surgery. Arch Med Sci Atheroscler Dis. 2020; 5: e320–31. DOI: 10.5114/amsad.2020.103377.
Fourdain S., Provost S., Tremblay J. et al. Functional brain connectivity after corrective cardiac surgery for critical congenital heart disease: a preliminary near-infrared spectroscopy (NIRS) report. Child Neuropsychol. 2023; 29(7): 1088–1108. DOI: 10.1080/09297049.2023.2170340.
Massey S.L., Weinerman B., Naim M.Y. Perioperative neuromonitoring in children with congenital heart disease. Neurocrit Care. 2023. DOI: 10.1007/s12028-023-01737-x.
Abubakar M.O., Zanelli S.A., Spaeder M.C. Changes in cerebral regional oxygen saturation variability in neonates undergoing cardiac surgery: a prospective cohort study. Pediatr Cardiol. 2023; 44(7): 1560–5. DOI: 10.1007/s00246-023-03239-1.
Altun D., Doğan A., Arnaz A. et al. Noninvasive monitoring of central venous oxygen saturation by jugular transcutaneous near-infrared spectroscopy in pediatric patients undergoing congenital cardiac surgery. Turk J Med Sci. 2020; 50(5): 1280–7. DOI: 10.3906/sag-1911-135.
Gillam-Krakauer M. et al. Correlation of abdominal rSO2 with superior mesenteric artery velocities in preterm infants. J. Perinatol. 2013; 33(8): 609–12.
Mishra V., Mathur A.A., Mohamed S., Maheshwari A. Role of Near-infrared Spectroscopy in the Diagnosis and Assessment of Necrotizing Enterocolitis. Newborn (Clarksville). 2022; 1(1): 177–81. DOI: 10.5005/jp-journals-11002-0001.
Özkan H., Çetinkaya M., Dorum B.A., Köksal N. Mesenteric tissue oxygenation status on the development of necrotizing enterocolitis. Turk J Pediatr. 2021; 63(5): 811–7. DOI: 10.24953/turkjped.2021.05.009.
Casals A.J., Spaeder M.C. Association of early postoperative regional oxygen saturation measures and development of necrotizing enterocolitis in neonates following cardiac surgery. Pediatr Cardiol. 2023. DOI: 10.1007/s00246-023-03117-w.
DeWitt A.G. et al. Splanchnic near-infrared spectroscopy and risk of necrotizing enterocolitis after neonatal heart surgery. Pediatr Cardiol. 2014; 35(7): 286–94.
Neu J. Gastroenterology and nutrition: neonatology questions and controversies. 2nd ed. Philadelphia: Elsevier; Saunders. 2012: 361.
Dodge-Khatami J., Gottschalk U., Eulenburg C. et al. Prognostic value of perioperative near-infrared spectroscopy during neonatal and infant congenital heart surgery for adverse in-hospital clinical events. World J Pediatr Congenit Heart Surg. 2012; 3: 221–8. DOI: 10.1177/2150135111426298.
Harer M.W., Chock V.Y. Renal tissue oxygenation monitoring-an opportunity to improve kidney outcomes in the vulnerable neonatal population. Front Pediatr. 2020; 8: 241. DOI: 10.3389/fped.2020.00241.
Greisen G., Leung T., Wolf M. Has the time come to use near-infrared spectroscopy as a routine clinical tool in preterm infants undergoing intensive care? Philos Trans A Math Phys Eng Sci. 2011; 369(1955): 4440–51. DOI: 10.1098/rsta.2011.0261.
McNeill S., Gatenby J.C., McElroy S., Engelhardt B. Normal cerebral, renal and abdominal regional oxygen saturations using near-infrared spectroscopy in preterm infants. J Perinatol. 2011; 31: 51–7. 10.1038/jp.2010.71.
Richter A.E., Schat T.E., Van Braeckel K.N. et al. The effect of maternal antihypertensive drugs on the cerebral, renal and splanchnic tissue oxygen extraction of preterm neonates. Neonatology. 2016; 110(3): 163–71. DOI: 10.1159/000445283.