Study of cytokines in the blood of pregnant women with asthma

Abstract

Extragenital mother's disease interfere with the normal fetal development may lead to his illness or even death (1). Asthma is a disease with a complex polyetiological pathogenesis, which isbased on chronic persistent allergic inflammation of the bronchi and hyperreactivity (2). Cytokines - a signaling molecules that play a key role in the immune system in health and disease (3). It is recognized that in asthma increased serum such as the cytokines IL-1, TNF-α, IL-4, IL-5, IL-6, IL-8, IL-13, IL-18 (4.5). Had higher levels of several cytokines in exacerbation and severe asthma, so you can use this indicator to evaluate the effectiveness of treatment and individualisation of pathogenetic therapy.