DIC-SYNDROME IN CHILDREN WITH CONGENITAL HEART DISEASES: MORPHOLOGICAL PICTURE OF CHANGES IN THE MICROCIRCULATORY BED
Abstract
Currently, the problem of congenital heart defects (CHD) in children, it is one of the most relevant in pediatric cardiology, which is due to the progressive increase in the number of children suffering from this pathology. CHD is present in almost 1 % of children born and is the main category among all congenital anomalies. Based on the analysis of the autopsy material of the PAO “Clinic of SPbGPMU”, it should be noted that the most common cause of death in children in the postoperative period was the development of acute cardiovascular insufficiency, which, according to the histological examination of the biopsy material, was accompanied by DIC syndrome. The risk factors that provoke the development of DIC syndrome in cardiac surgery patients, as well as the pathophysiological mechanisms of the damaging effect of artificial blood circulation during cardiac surgery, were determined.