Infectious pathology in patients after radical correction of congenital heart disease

Abstract

The article highlights the frequency of occurrence of clinical and laboratory manifestations of the infectious process in children operated on for congenital heart defects. The results of bacterological studies of crops from various loci (venous blood, central venous catheter, arterial catheter, tracheobronchial tree, pharynx and nose, stomach contents, feces, urine) in children are analyzed and brought together. It was established that in the presented sample the most frequent were patients with ventricular septal defect (VSD) - 18,27%, atrial septal defect (ASD) - 12,9%, open arterial duct (OAD) - 11,82%. Less common were patients with complex congenital heart defects: hypoplastic left heart syndrome (HLHS) - 8,6%, aortic coarctation (CA) - 5,3%, transposition of the great vessels (TGV) - 5,3%, pulmonary atresia (PA) - 5,3%. Fallot's tetrad and total abnormal drainage of pulmonary veins were found in 4,3% of cases. The rarest defects were: double separation of vessels from the right ventricle, atrioventricular communication, common arterial trunk - 2,1% each, and functionally single ventricle - 1,07%. In 47 patients (68%) a radical correction of the defect was performed. In 26 patients (37,6%), clinical manifestations of an infectious process were noted. In 31 patients (44,9%), laboratory manifestations of an infectious process were noted. According to the results of bacteriological studies, the most often positive seeding was observed from the tracheobronchial tree, feces and gastric contents (gram-negative flora), and least often from venous blood (gram-positive flora).