CURRENT ROLE OF CAPTOPRIL-RENOSCINTIGRAPHY IN THE DIFFERENTIAL DIAGNOSIS OF RENOVASCULAR HYPERTENSION IN PATIENTS WITH CHRONIC KIDNEY DISEASE
Abstract
Chronic kidney disease (CKD) is a globally significant health problem, reaching a population prevalence of approximately 15%. An important risk factor for CKD is the growth and progression of arterial hypertension (AH), due to the vicious circle of cause-and-effect relationships of these pathologies. Hypertension in patients with CKD occurs in 70% of cases. Almost 90% of patients suffer from hypertension in the later stages of CKD. Comparison of separate renal function before and after captopril is the simplest and most commonly used semi-quantitative parameter to assess changes in renal function. This parameter is quite sensitive in patients with unilateral functionally significant renal artery stenosis. Captopril renography is an important diagnostic test. It plays a role in the differential diagnosis of treatable renovascular hypertension and may play a large and far-reaching role in assessing the safety of angiotensin-converting enzyme inhibitor therapy in patients with reduced renal function and hypertension.
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