DIFFICULTIES OF VISUALIZATION WITH VARIOUS METHODS OF RADIATION RESEARCH

Abstract

Osteoid osteoma is a benign tumor of osteogenic origin that causes gradually increasing aching pains, unlike other benign tumors. A number of domestic authors speak in favor of belonging of this tumor to a special type of chronic non-purulent osteomyelitis in terms of the X-ray picture, which is also characterized by a central focus of osteonecrosis. It is quite easily diagnosed radiographically, however, in the absence of changes on radiographs and the preservation of clinical symptoms, a comprehensive radiological examination is necessary. The progress and intensive use of chemotherapy in the treatment of cancer in children has led to an increase in the number of such patients who survived cancer in childhood and subsequently faced an increased risk of diseases of the musculoskeletal system. However, the underlying mechanisms of chemotherapy-induced skeletal defects remain largely unclear. High doses of glucocorticoids and cytostatics can cause growth plate dysfunction, damage osteogenesis progenitor cells, suppress bone formation, and increase bone resorption and marrow adipogenesis, leading to total bone loss. It cannot be ruled out that the appearance of osteoid osteoma after chemotherapy treatment in children with cancer is a long-term consequence of this treatment. This requires increased attention from both clinicians and radiologists. It is also necessary to further study this issue in search of the selection of therapy that would minimize such serious consequences.