THE EFFECT OF PRENATAL EXPOSURE TO SMALL DOSES OF GAMMA RADIATION ON THE STRUCTURE OF THE THYMUS OF OFFSPRING

  • Olga Yu Smirnova Saint-Petersburg State Pediatric Medical University 194100, Saint-Рetersburg
  • Anna V Zaitseva Saint-Petersburg State Pediatric Medical University 194100, Saint-Рetersburg
  • Linard Yu Artyukh Saint-Petersburg State Pediatric Medical University 194100, Saint-Рetersburg
  • Natalia R Karelina Saint-Petersburg State Pediatric Medical University 194100, Saint-Рetersburg
Keywords: thymus, immune system, gamma irradiation

Abstract

Most of the studies on the biological effectiveness of irradiation are devoted to changes in the immune system resulting from exposure to the radiation factor in the range of high doses. This article presents a study of the effect of total doses of gamma irradiation of 5 and 75 sGr on the developing thymus. The study was conducted on fruits obtained from healthy white mongrel rats. The animals were divided into 3 groups: a physiological control group (FC, or intact animals), animals exposed to fractionated exposure to radiation at a total dose of 5 sGr, animals exposed to fractionated exposure to gamma radiation at a total dose of 75 sGr. Analysis of the data obtained allows us to conclude that fractionated irradiation at a relatively low total dose (5 sGr) does not generally disrupt the morphogenesis process of the central organ of the immune system.

Author Biographies

Olga Yu Smirnova, Saint-Petersburg State Pediatric Medical University 194100, Saint-Рetersburg
Litovskaya str., 2; Candidate of Medical Sciences, Associate Professor of the Department of Human Anatomy
Anna V Zaitseva, Saint-Petersburg State Pediatric Medical University 194100, Saint-Рetersburg
Litovskaya str., 2
Linard Yu Artyukh, Saint-Petersburg State Pediatric Medical University 194100, Saint-Рetersburg
Litovskaya str., 2
Natalia R Karelina, Saint-Petersburg State Pediatric Medical University 194100, Saint-Рetersburg
Litovskaya str., 2
Published
2022-08-30
How to Cite
Smirnova, O. Y., Zaitseva, A. V., Artyukh, L. Y., & Karelina, N. R. (2022). THE EFFECT OF PRENATAL EXPOSURE TO SMALL DOSES OF GAMMA RADIATION ON THE STRUCTURE OF THE THYMUS OF OFFSPRING. FORCIPE, 5(2), 4-10. Retrieved from https://ojs3.gpmu.org/index.php/forcipe/article/view/4156
Section
Статьи