EFFICACY AND SAFETY OF EXTRACORPOREAL SHOCKWAVE THERAPY FOR THE TREATMENT OF CHRONIC NON-BACTERIAL PROSTATITIS: SYSTEMATIC REVIEW AND META-ANALYSIS
Abstract
Background. Chronic abacterial prostatitis is the most common urological disease compared to chronic bacterial prostatitis. According to WHO, urologists diagnose chronic prostatitis in every tenth patient; the incidence of chronic bacterial prostatitis is 6–10%, and chronic abacterial prostatitis is 80–90%, and acute bacterial prostatitis occurs in 3–5% of cases. Materials and methods. The research was collected using four search engines — PubMed, Cochrane, Science Direct and EBSCO Host. Data up to 2020 were evaluated based on predefined inclusion and exclusion criteria. The selection of materials for the study was carried out by two reviewers. The studies were then analyzed. Results. 74 publications were initially retrieved, and 3 studies were considered for both qualitative and quantitative analyses. In these studies, after 12 weeks of treatment, we found that the use of shock wave therapy was significantly associated with a decrease in the pain area (mean difference: –3.93; 95% confidence interval [CI] –5.13, –2.73; p <0.001), improvement in urine parameters (mean difference: –1.79; 95% CI –2.38, –1.21; p <0.001), quality of life (average difference: –1.71; 95% CI –2.12, –1.31; p <0.001) and the index of symptoms of chronic prostatitis of the National Institutes of Health (NIHCPSI (see below)) (average difference: –5.45; 95% CI –5.74, –5.16; p <0.001). Conclusions. Shock wave therapy is effective and safe for reducing pain and improving urination, assessing NIHCPSI and quality of life in patients with chronic abacterial prostatitis.
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