POST-TRAUMATIC STRESS DISORDER ASSOCIATED WITH PREGNANCY AND CHILDBIRTH: DEFINITIONS, MODERN CONCEPTS, PATHOPHYSIOLOGICAL MECHANISMS, RISK FACTORS, DIAGNOSIS

  • E.V. Kozhadey Saint Petersburg State Pediatric Medical University. Lithuania 2, Saint Petersburg, Russian Federation, 194100 https://orcid.org/0009-0005-7552-8533
  • A.G. Vasilyev Saint Petersburg State Pediatric Medical University. Lithuania 2, Saint Petersburg, Russian Federation, 194100
Keywords: post-traumatic stress disorder, postpartum post-traumatic stress disorder, perinatal loss, postpartum period, traumatic birth

Abstract

The review focuses on post-traumatic stress disorder associated with pregnancy and childbirth. In the literature, there is the concept of post-traumatic stress disorder associated with pregnancy and childbirth, which describes mental disorders in parents during the period from the beginning of pregnancy to 12 months after childbirth. In contrast to the classical concept of post-traumatic stress disorder, this term is used in most cases in relation to the mother, less often in relation to the father of the child, in the presence of traumatic events associated with pregnancy and childbirth, starting from the beginning of pregnancy and up to 1 year after childbirth. The uniqueness of this term is emphasized from the perspective of mental disorders in parents associated with traumatic events during pregnancy, childbirth and the subsequent fate and prognosis for a premature child and/or a child with pathology. Data is provided on the complexities of terminology used to describe traumatic events from the beginning of pregnancy to 12 months after childbirth. Information is presented on the prevalence of stressful conditions during the period associated with pregnancy and childbirth in parents, risk factors are described in detail, including obstetric, socio-economic, pathophysiological, and psychiatric. The stressful conditions of parents whose children are in the intensive care unit are described separately, with a description of the parents’ reactions to different outcomes of the child’s hospitalization. Options for the prevention of stressful conditions in parents are highlighted, and recommendations are provided for identifying patients suffering from post-traumatic stress disorder associated with pregnancy and childbirth, and for the interaction of maternity workers with this group of patients.

References

Нуллер Ю.Л., Циркин. Международная классификация болезней 10-го пересмотра. Классификация психических и поведенческих расстройств. Клиническое описание и указания по диа­гностике. СПб.: Адис; 1994.

American Psychiatric Association Diagnostic And Statistical Manual Of Mental Disorders, 5th Edition DSM 5. Washington. American Psychiatric Publishing; 2013.

Austin M.P. Classification of mental health disorders in the perinatal period: future directions for DSM-V and ICD-11. Arch Womens Ment Health. 2010; 1(1): 41–4. DOI: 10.1007/s00737-009-0110-5.

Baransel E.S., Uçar T. Posttraumatic stress and affecting factors in couples after perinatal loss: A Turkish sample. Perspect Psychiatr Care. 2020; 56(1): 112–20. DOI: 10.1111/ppc.12390.

Beck C.T. Posttraumatic Stress Disorder After Birth: A Metaphor Analysis. MCN Am J Matern Child Nurs. 2016; 41(2): 76–83. DOI: 10.1097/NMC.0000000000000211.

Callahan J.L., Borja S.E. Psychological outcomes and measurement of maternal posttraumatic stress disorder during the perinatal period. J Perinat Neonatal Nurs. 2008; 22(1): 49–9. DOI: 10.1097/01.JPN.0000311875.38452.26.

Çankaya S., Dikmen H.A. The relationship between posttraumatic stress symptoms of maternity professionals and quality of work life, cognitive status, and traumatic perinatal experiences. Arch Psychiatr Nurs. 2020; 34(4): 251–60. DOI: 10.1016/j.apnu.2020.04.002.

Cirino N.H., Knapp J.M. Perinatal Posttraumatic Stress Disorder: A Review of Risk Factors, Diagnosis, and Treatment. Obstet Gynecol Surv. 2019; 74(6): 369–76. DOI: 10.1097/OGX.0000000000000680.

Cook N., Ayers S., Horsch A. Maternal posttraumatic stress disorder during the perinatal period and child outcomes: A systematic review. J Affect Disord. 2018; 225(1): 18–31. DOI: 10.1016/j.jad.2017.07.045.

Daugirdaite V., van den Akker O., Purewal S. Posttraumatic Stress and Posttraumatic Stress Disorder after Termination of Pregnancy and Reproductive Loss: A Systematic Review. Journal of Pregnancy. 2015: 1–14. DOI: 10.1155/2015/646345.

Erickson N., Julian M., Muzik M. Perinatal depression, PTSD, and trauma: Impact on mother-infant attachment and interventions to mitigate the transmission of risk. Int Rev Psychiatry. 2019; 31(3): 245–63. DOI: 10.1080/09540261.2018.1563529.

Fernández-Ordoñez E., González-Cano-Caballero M., Guerra-Marmolejo C. et al. Perinatal Grief and Post-Traumatic Stress Disorder in Pregnancy after Perinatal Loss: A Longitudinal Study Protocol. Int J Environ Res Public Health. 2021; 18(6): 1–6. DOI: 10.3390/ijerph18062874.

Geller P.A., Stasko E.C. Effect of Previous Posttraumatic Stress in the Perinatal Period. J Obstet Gynecol Neonatal Nurs. 2017; 46(6): 912–22. DOI: 10.1016/j.jogn.2017.04.136.

Granner J.R., Seng J.S. Using Theories of Posttraumatic Stress to Inform Perinatal Care Clinician Responses to Trauma Reactions. J Midwifery Womens Health. 2021; 66(5): 567–78. DOI: 10.1111/jmwh.13287.

Grekin R., O’Hara M.W., Brock R.L. A model of risk for perinatal posttraumatic stress symptoms. Arch Womens Ment Health. 2021; 24(2): 259–70. DOI: 10.1007/s00737-020-01068-2.

Habersaat S., Borghini A., Nessi J. et al. Effects of perinatal stress and maternal traumatic stress on the cortisol regulation of preterm infants. J Trauma Stress. 2014; 27(4): 488–91. DOI: 10.1002/jts.21939.

Harrison S.E., Ayers S., Quigley M.A. et al. Prevalence and factors associated with postpartum posttraumatic stress in a population-based maternity survey in England. J Affect Disord. 2021; 279: 749–56. DOI: 10.1016/j.jad.2020.11.102.

Helle N., Barkmann C., Ehrhardt S., Bindt C. Postpartum posttraumatic and acute stress in mothers and fathers of infants with very low birth weight: Cross-sectional results from a controlled multicenter cohort study. J Affect Disord. 2018; 235: 467–73.

DOI: 10.1016/j.jad.2018.04.013.

Hernández-Martínez A., Rodríguez-Almagro J., Molina-Alarcón M. et al. Postpartum post-traumatic stress disorder: Associated perinatal factors and quality of life. J Affect Disord. 2019; 249: 143–50. DOI: 10.1016/j.jad.2019.01.042.

Hernández-Martínez A., Rodríguez-Almagro J., Molina-Alarcón M. et al. Perinatal factors related to post-traumatic stress disorder symptoms 1-5 years following birth. Women Birth. 2020; 33(2): 129–35. DOI: 10.1016/j.wombi.2019.03.008.

Krosch D.J., Shakespeare-Finch J. Grief, traumatic stress,

and posttraumatic growth in women who have experienced pregnancy loss. Psychol Trauma. 2017; 9(4): 425–33. DOI: 10.1037/tra0000183.

Liu C.H., Erdei C., Mittal L. Risk factors for depression, anxiety, and PTSD symptoms in perinatal women during the COVID-19 Pandemic. Psychiatry Res. 2021; 295: 1–18. DOI: 10.1016/j.psychres.2020.113552.

Liu Y., Zhang L., Guo N., Jiang H. Postpartum depression and postpartum post-traumatic stress disorder: prevalence and associated factors. BMC Psychiatry. 2021; 21(1): 1–11. DOI: 10.1186/s12888-021-03432-7.

Malin K.J., Johnson T.S., McAndrew S. et al. Infant illness severity and perinatal post-traumatic stress disorder after discharge from the neonatal intensive care unit. Early Hum Dev. 2020; 140: 1–18. DOI: 10.1016/j.earlhumdev.2019.104930.

Matsumoto K., Sato K., Hamatani S. et al. Cognitive behavioral therapy for postpartum panic disorder: a case series. MC Psychol. 2019; 7(1): 1–14. DOI: 10.1186/s40359-019-0330-z.

Meltzer-Brody S., Howard L.M., Bergink V. et al. Postpartum psychiatric disorders. Nat Rev Dis Primers. 2018; 4: 1–18. DOI: 10.1038/nrdp.2018.22.

Nillni Y.I., Mehralizade A., Mayer L., Milanovic S. Treatment of depression, anxiety, and trauma-related disorders during the perinatal period: A systematic review. Clin Psychol Rev. 2018; 66: 136–48. DOI: 10.1016/j.cpr.2018.06.004.

Nillni Y.I., Shayani D.R., Finley E. et al. The Impact of Posttrauma­tic Stress Disorder and Moral Injury on Women Veterans’ Perinatal Outcomes Following Separation From Military Service. J Trauma Stress. 2020; 33(3): 248–56. DOI: 10.1002/jts.22509.

Pourmovahed Z., Yassini Ardekani S.M., Roozbeh B., Ezabad A.R. The Effect of Non-verbal Music on Posttraumatic Stress Disorder in Mothers of Premature Neonates. Iran J Nurs Midwifery Res. 2021; 26(2): 150–3. DOI: 10.4103/ijnmr.IJNMR_37_20.

Robertson E., Grace S., Wallington T., Stewart D.E. Antenatal risk factors for postpartum depression: a synthesis of recent literature. Gen Hosp Psychiatry. 2004; 26(4): 289–95. DOI: 10.1016/j.genhosppsych.2004.02.006.

Seng J.S., Kohn-Wood L.P., McPherson M.D., Sperlich M. Disparity in posttraumatic stress disorder diagnosis among African American pregnant women. Arch Womens Ment Health. 2011; 14(4): 295–306. DOI: 10.1007/s00737-011-0218-2.

Sheen K., Spiby H., Slade P. Exposure to traumatic perinatal experiences and posttraumatic stress symptoms in midwives: prevalence and association with burnout. Int J Nurs Stud. 2015; 52(2): 578–87. DOI: 10.1016/j.ijnurstu.2014.11.006.

Shivakumar G., Anderson E.H., Surís A.M. Managing posttraumatic stress disorder and major depression in women veterans during the perinatal period. J Womens Health (Larchmt). 2015; 24(1): 18–22. DOI: 10.1089/jwh.2013.4664.

Speisman B.B., Storch E.A., Abramowitz J.S. Postpartum obsessive-compulsive disorder. J Obstet Gynecol Neonatal Nurs. 2011; 40(6): 680–90. DOI: 10.1111/j.1552-6909.2011.01294.x.

Thomas J.L., Cleveland S., Pietrzak R.H.et al. Elucidating posttraumatic stress symptom dimensions and health correlates among postpartum women. J Affect Disord. 2021; 294: 314–21. DOI: 10.1016/j.jad.2021.07.025.

Thomson M., Sharma V. Pharmacotherapeutic considerations for the treatment of posttraumatic stress disorder during and after pregnancy. Expert Opin Pharmacother. 2021; 22(6): 705–14. DOI: 10.1080/14656566.2020.1854727.

Vignato J., Connelly C.D., Bush R.A. et al. Correlates of Perinatal Post-Traumatic Stress among Culturally Diverse Women with Depressive Symptomatology. Issues Ment Health Nurs. 2018; 39(10): 840–9. DOI: 10.1080/01612840.2018.1488313.

Vignato J., Georges J.M., Bush R.A., Connelly C.D. Post-traumatic stress disorder in the perinatal period: A concept analysis. J Clin Nurs. 2017; 26(23–24): 3859–68. DOI: 10.1111/jocn.13800.

Yildiz P.D., Ayers S., Phillips L. The prevalence of posttraumatic stress disorder in pregnancy and after birth: A systematic review and meta-ana­lysis. J Affect Disord. 2017; 208: 634–45. DOI: 10.1016/j.jad.2016.10.009.

Zhang D., Zhang J., Gan Q.et al. Validating the Psychometric Chara­cteristics of the Perinatal Posttraumatic Stress Disorder Questionnaire (PPQ) in a Chinese Context. Arch Psychiatr Nurs. 2018; 32(1): 57–61. DOI: 10.1016/j.apnu.2017.09.016.

Published
2024-05-15
How to Cite
Kozhadey, E., & Vasilyev, A. (2024). POST-TRAUMATIC STRESS DISORDER ASSOCIATED WITH PREGNANCY AND CHILDBIRTH: DEFINITIONS, MODERN CONCEPTS, PATHOPHYSIOLOGICAL MECHANISMS, RISK FACTORS, DIAGNOSIS. Russian Biomedical Research, 8(4), 74-84. https://doi.org/10.56871/RBR.2023.84.68.009
Section
Статьи

Most read articles by the same author(s)