LATENT VIRAL INFECTIONS IN BURNED PATIENTS WITH DEEP BURNS, STATE OF THE PROBLEM

  • E.V. Zinoviev Saint Petersburg institute of emergency care named after I.I. Dzhanelidze. Budapeshtskaya st. 3, Saint Petersburg, Russian Federation, 192242
  • L.P. Pivovarova Saint Petersburg institute of emergency care named after I.I. Dzhanelidze. Budapeshtskaya st. 3, Saint Petersburg, Russian Federation, 192242
  • V.A. Manukovsky Saint Petersburg institute of emergency care named after I.I. Dzhanelidze. Budapeshtskaya st. 3, Saint Petersburg, Russian Federation, 192242
  • V.V. Soloshenko Saint Petersburg institute of emergency care named after I.I. Dzhanelidze. Budapeshtskaya st. 3, Saint Petersburg, Russian Federation, 192242
  • D.V. Kostyakov Saint Petersburg institute of emergency care named after I.I. Dzhanelidze. Budapeshtskaya st. 3, Saint Petersburg, Russian Federation, 192242
  • V.N. Yurina Saint Petersburg institute of emergency care named after I.I. Dzhanelidze. Budapeshtskaya st. 3, Saint Petersburg, Russian Federation, 192242
  • A.V. Semiglazov Saint Petersburg institute of emergency care named after I.I. Dzhanelidze. Budapeshtskaya st. 3, Saint Petersburg, Russian Federation, 192242
  • S.N. Pyatakov City Clinical Hospital № 4 of the Sochi City Health Department. Tuapsinskaya st., 1, Krasnodar region, Sochi, Russian Federation, 354057
  • R.V. Korablev Saint Petersburg State Pediatric Medical University. Lithuania 2, Saint Petersburg, Russian Federation, 194100
Keywords: burns, deep burns, immunosuppression, viruses, herpes virus, chickenpox, cytomegalovirus, Epstein–Barr virus

Abstract

This review presents an analysis of the treatment of patients with extensive deep skin burns, since it is the severity of the burn injury that is the main condition for the development of immunosuppression, the activation of latent viral infections, which leads to severe complications of burn disease. Over the past 3 years, all medical institutions have encountered a new coronavirus infection SARS-CoV-2. In the burn departments, it was characterized by specific changes in the immune status. The purpose of this review was to summarize data on the effect of various types of latent viruses on the course of burn disease in patients with extensive deep burns. In the course of the work, the features of the impact on the course of the wound process and the results of skin plasty of the human herpes virus family, varicella-zoster virus, cytomegalovirus, and Epstein-Barr viruses were analyzed. It has been established that the manifestations of a viral infection are diverse, the effect on the body of a severely burned person is multifaceted, and the information received from various authors is contradictory. Given the annual increase in the number of such victims being treated in intensive care units, active screening studies are required to identify viral infections and determine their impact on the course of burn disease.

Published
2023-08-31
How to Cite
Zinoviev, E., Pivovarova, L., Manukovsky, V., Soloshenko, V., Kostyakov, D., Yurina, V., Semiglazov, A., Pyatakov, S., & Korablev, R. (2023). LATENT VIRAL INFECTIONS IN BURNED PATIENTS WITH DEEP BURNS, STATE OF THE PROBLEM. Russian Biomedical Research, 8(2), 55-63. https://doi.org/10.56871/RBR.2023.40.89.008
Section
Статьи

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